Unit of Maternal-Fetal-Medicine, Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrake, 8100 Alexandroupolis, Greece.
Third Department of Obstetrics and Gynecology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Medicina (Kaunas). 2024 Oct 15;60(10):1691. doi: 10.3390/medicina60101691.
The use of cannabis during pregnancy has emerged as a mounting cause for concern due to its potential adverse consequences on both the mother and her offspring. This review will focus on the dangers associated with prenatal exposure to cannabis, particularly those related to neurodevelopment. It will also discuss the features of maternal and placental functioning that are likely to have long-term effects on the offspring's development. The most pertinent and up-to-date materials can be found through a literature search. The literature emphasizes the substantial hazards associated with prenatal exposure to cannabis. These include impairments in cognitive function and difficulties in behavior in this particular instance. Structural and functional alterations in the brain can be noticed in offspring. The use of cannabis has been associated with an increased likelihood of experiencing pregnancy-related complications, such as giving birth prematurely and having a baby with a low birth weight. Additionally, it has been connected to potential negative effects on mental and emotional well-being. Studies have shown that when a pregnant woman is exposed to cannabis, it can negatively impact the functioning of the placenta and the growth of the fetus. This might potentially contribute to the development of placental insufficiency and restricted growth in the womb. Longitudinal studies reveal that children who were exposed to cannabis in the womb experience additional long-term developmental challenges, such as decreased cognitive abilities, reduced academic performance, and behavioral issues. In order to address the problem of cannabis usage during pregnancy, it is essential to adopt a comprehensive and coordinated strategy. This method should integrate and synchronize public health policy, education, and research initiatives. By implementing these targeted strategies, it is possible to mitigate potential health and welfare concerns for both present and future generations.
怀孕期间使用大麻已成为一个日益令人担忧的问题,因为它可能对母亲及其后代产生不良后果。本次综述将重点关注产前接触大麻与神经发育相关的危害。还将讨论母体和胎盘功能的特征,这些特征可能对后代的发育产生长期影响。通过文献检索可以找到最新和最相关的材料。文献强调了产前接触大麻的重大危害。这些危害包括在认知功能和行为方面的损害。在后代中可以观察到大脑的结构和功能改变。使用大麻与妊娠相关并发症的发生几率增加有关,例如早产和低出生体重儿。此外,它还与心理健康和情感健康的潜在负面影响有关。研究表明,孕妇接触大麻会对胎盘功能和胎儿生长产生负面影响。这可能导致胎盘功能不全和子宫内生长受限。纵向研究表明,在子宫内接触大麻的儿童会面临额外的长期发育挑战,例如认知能力下降、学业成绩下降和行为问题。为了解决怀孕期间使用大麻的问题,必须采取全面协调的策略。这种方法应整合和同步公共卫生政策、教育和研究计划。通过实施这些有针对性的策略,可以减轻当前和未来几代人的潜在健康和福利问题。