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石榴提取物对女性生殖健康和乳腺癌的治疗潜力

Therapeutic Potential of Pomegranate Extract for Women's Reproductive Health and Breast Cancer.

作者信息

Jang Jung Yoon, Kim Donghwan, Im Eunok, Kim Nam Deuk

机构信息

Department of Pharmacy, College of Pharmacy, Research Institute for Drug Development, Pusan National University, Busan 46241, Republic of Korea.

Functional Food Materials Research Group, Korea Food Research Institute, Wanju-gun 55365, Jeollabuk-do, Republic of Korea.

出版信息

Life (Basel). 2024 Oct 3;14(10):1264. doi: 10.3390/life14101264.

Abstract

Pomegranate extract has potential benefits for women's reproductive health, including fertility enhancement, menstrual cycle regulation, pregnancy support, and polycystic ovary syndrome (PCOS) treatment. It possesses antioxidant properties, reducing oxidative stress and improving fertility. Pomegranate extract may help regulate hormonal imbalances and promote regular menstrual cycles. The extract's rich nutrient profile supports placental development and fetal growth and may reduce the risk of preterm birth. Additionally, pomegranate extract shows promise in improving insulin sensitivity and reducing inflammation and oxidative damage in PCOS. Some studies suggest its potential anticancer properties, particularly against breast cancer. However, further research, including human clinical trials, is necessary to establish its effectiveness and safety. The current evidence is limited and primarily based on in vitro studies, animal studies, and clinical trials. This review provides a comprehensive summary of the benefits of pomegranate extract for women's reproductive health and breast cancer, serving as a reference for future research.

摘要

石榴提取物对女性生殖健康具有潜在益处,包括提高生育能力、调节月经周期、支持孕期以及治疗多囊卵巢综合征(PCOS)。它具有抗氧化特性,可减轻氧化应激并改善生育能力。石榴提取物可能有助于调节激素失衡并促进规律的月经周期。该提取物丰富的营养成分有助于胎盘发育和胎儿生长,并可能降低早产风险。此外,石榴提取物在改善胰岛素敏感性以及减轻PCOS中的炎症和氧化损伤方面显示出前景。一些研究表明其具有潜在的抗癌特性,尤其是对乳腺癌。然而,需要进一步的研究,包括人体临床试验,来确定其有效性和安全性。目前的证据有限,主要基于体外研究、动物研究和临床试验。本综述全面总结了石榴提取物对女性生殖健康和乳腺癌的益处,可为未来研究提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab4/11509572/d33a2069a13c/life-14-01264-g001.jpg

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