Mazzocchi G, Robba C, Rebuffat P, Nussdorfer G G
Acta Endocrinol (Copenh). 1986 Jan;111(1):101-5. doi: 10.1530/acta.0.1110101.
The effects of short and prolonged treatments with prolactin on the morphology and hormone secretion of the rat adrenal zona glomerulosa were investigated by coupled morphometric and radioimmunological techniques. Short-term prolactin administration did not alter plasma aldosterone concentration or zona glomerulosa morphology. Conversely, chronic prolactin treatment caused both a notable hypertrophy of zona glomerulosa cells and a significant rise in the blood level of aldosterone. The possibility is discussed that prolactin may be involved in the control of the growth and steroidogenic capacity of the rat adrenal zona glomerulosa.
通过形态计量学和放射免疫技术相结合的方法，研究了催乳素短期和长期处理对大鼠肾上腺球状带形态和激素分泌的影响。短期给予催乳素并未改变血浆醛固酮浓度或球状带形态。相反，慢性催乳素处理导致球状带细胞显著肥大以及醛固酮血水平显著升高。文中讨论了催乳素可能参与大鼠肾上腺球状带生长和类固醇生成能力调控的可能性。
