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雅温得两所教学医院慢性硬脑膜下血肿的预后因素。

Prognostic factors of chronic subdural hematomas in two reference university teaching hospitals in the city of Yaounde.

机构信息

Department of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon; Yaounde General Hospital, Yaounde, Cameroon.

Department of Surgery and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.

出版信息

Clin Neurol Neurosurg. 2024 Dec;247:108614. doi: 10.1016/j.clineuro.2024.108614. Epub 2024 Oct 22.

Abstract

OBJECTIVES

Despite the good prognosis of surgical treatment of chronic subdural hematomas, there are some early deaths, recurrences and post-operative complications. The objective of this study is to analyze the prognostic factors of chronic subdural hematomas in two reference university teaching hospitals in the city of Yaounde.

METHOD

Three hundred and ten cases of chronic subdural hematomas were diagnosed on 3788 patients hospitalized in the neurosurgery departments of two reference university teaching hospitals in the city of Yaounde from January 1st, 2015 to December 31st, 2021 (7 years). The authors collected data from patients in whom surgical treatment was performed and assessed their prognosis with regard to the rate of early and late recurrence, mortality rate and postoperative complications and associated factors.

RESULTS

Data from 284 patients were analyzed. The mortality rate was 6.7 % and the recurrence rate was 3.2 % in early postoperative period and 4.5 % after a follow-up of 3-24 months. Prognostic factors for death were age greater than or equal to 80 years (p value = 0.034) and presence of cortico-subcortical atrophy (p value = 0.003). The main recurrence factors were age greater than or equal to 70 years and compartmentalization of the hematoma.

CONCLUSION

Chronic subdural hematomas are generally of good prognosis when the Glasgow coma score on admission is good and adequate management is carried out as soon as possible. Advanced age, lesions such as cortico-subcortical atrophy and compartmentalization of the hematoma are all factors that predispose to recurrence or early mortality. Those groups of patients should therefore benefit from a closer follow-up in post-operative period.

摘要

目的

尽管慢性硬膜下血肿的手术治疗预后良好,但仍存在一些早期死亡、复发和术后并发症。本研究旨在分析雅温得市两家教学参考医院的慢性硬膜下血肿的预后因素。

方法

2015 年 1 月 1 日至 2021 年 12 月 31 日(7 年),作者在雅温得市两家教学参考医院神经外科共收治 3788 例住院患者,诊断出 310 例慢性硬膜下血肿。作者收集了接受手术治疗患者的数据,并评估了其早期和晚期复发率、死亡率以及术后并发症的发生率和相关因素。

结果

分析了 284 例患者的数据。术后早期死亡率为 6.7%,3-24 个月随访时复发率为 3.2%。死亡的预后因素为年龄≥80 岁(p 值=0.034)和皮质下萎缩(p 值=0.003)。主要复发因素为年龄≥70 岁和血肿分隔。

结论

当入院时格拉斯哥昏迷评分良好且尽快进行充分治疗时,慢性硬膜下血肿的预后通常较好。高龄、皮质下萎缩等病变以及血肿分隔是复发或早期死亡的易患因素。这些患者群体在术后应接受更密切的随访。

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