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经皮硬膜下穿刺治疗慢性硬膜下血肿(青木法)后复发及并发症的相关因素:383例慢性硬膜下血肿患者的临床经验

Factors Related to Recurrence and Complications after Percutaneous Subdural Tapping for Chronic Subdural Hematomas (Aoki Method): Clinical Experiences of 383 Patients with Chronic Subdural Hematomas.

作者信息

Hamada Hiroaki, Tajitsu Kenichiro, Tokimura Hiroshi, Kuroki Shinichi, Hiwatari Takaaki, Hanaya Ryosuke

机构信息

Department of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University.

Department of Neurosurgery, Sendai Medical Association Hospital.

出版信息

Neurol Med Chir (Tokyo). 2025 Jun 15;65(6):263-270. doi: 10.2176/jns-nmc.2024-0224. Epub 2025 Apr 7.

Abstract

Chronic subdural hematoma is a common disease in the field of neurosurgery, and the number of cases is expected to continue increasing in an aging society. At our hospital, minimally invasive percutaneous subdural perforation (the Aoki method) is the first-line treatment. We investigated the recurrence rate associated with the Aoki method, factors related to recurrence, and the complication risks. Among the cases treated with the Aoki method between June 2007 and December 2020, 383 (431 lesions) for which image analysis and recurrence tracking were possible were included. On the basis of the preoperative patient background (sex, age, history of taking antiplatelet and anticoagulant drugs, preoperative neurological findings, imaging findings (preoperative hematoma volume and hematoma density), surgical details, and postoperative use of concomitant drugs), we retrospectively analyzed the recurrence rate, factors related to recurrence, and complication risk. The recurrence rate was 23.7%, which is within the same range as that of burr-hole hematoma irrigation. Multivariate analysis showed that age and a large preoperative hematoma volume were associated with recurrence. One of the 3 cases with postoperative epidural and 2 of the 3 cases with subdural hematomas required craniotomy. The incidence of complications requiring additional surgery was approximately 1%, which is comparable to that of burr-hole irrigation. The Aoki method is efficient because it is minimally invasive and has a therapeutic effect equivalent to that of burr-hole irrigation, which is the current standard of care.

摘要

慢性硬膜下血肿是神经外科领域的一种常见疾病,在老龄化社会中,病例数预计将持续增加。在我院,微创经皮硬膜下穿刺(青木法)是一线治疗方法。我们调查了与青木法相关的复发率、复发相关因素以及并发症风险。在2007年6月至2020年12月期间接受青木法治疗的病例中,纳入了383例(431个病灶)可进行图像分析和复发追踪的病例。基于术前患者背景(性别、年龄、服用抗血小板和抗凝药物的病史、术前神经学检查结果、影像学检查结果(术前血肿体积和血肿密度)、手术细节以及术后伴随药物的使用情况),我们回顾性分析了复发率、复发相关因素和并发症风险。复发率为23.7%,与钻孔血肿冲洗术的复发率处于同一范围。多因素分析表明,年龄和术前血肿体积较大与复发相关。3例术后硬膜外血肿患者中的1例以及3例硬膜下血肿患者中的2例需要开颅手术。需要额外手术的并发症发生率约为1%,与钻孔冲洗术相当。青木法具有微创性,且治疗效果与当前标准治疗方法钻孔冲洗术相当,因此是一种有效的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4207/12229747/2944700b4b46/1349-8029-65-6-0263-g001.jpg

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