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Innovative stroke intervention: Harnessing cerebral dopamine neurotrophic factor.

作者信息

Hou Dan, Yu Tao

机构信息

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.

出版信息

Mol Ther. 2024 Nov 6;32(11):3753-3755. doi: 10.1016/j.ymthe.2024.10.010. Epub 2024 Oct 26.

DOI:10.1016/j.ymthe.2024.10.010
PMID:39461333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11573738/
Abstract
摘要

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本文引用的文献

1
Targeting Rap1b signaling cascades with CDNF: Mitigating platelet activation, plasma oxylipins and reperfusion injury in stroke.靶向 Rap1b 信号级联反应与 CDNF：减轻血小板活化、血浆氧化脂质和脑卒中再灌注损伤。
Mol Ther. 2024 Nov 6;32(11):4021-4044. doi: 10.1016/j.ymthe.2024.09.005. Epub 2024 Sep 10.
2
CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress.CDNF 通过靶向内质网应激拯救肌萎缩侧索硬化症模型中的运动神经元。
Brain. 2023 Sep 1;146(9):3783-3799. doi: 10.1093/brain/awad087.
3
World Stroke Organization (WSO): Global Stroke Fact Sheet 2022.世界卒中组织（WSO）：全球卒中状况 2022 概要。
Int J Stroke. 2022 Jan;17(1):18-29. doi: 10.1177/17474930211065917.
4
Cerebral dopamine neurotrophic factor protects and repairs dopamine neurons by novel mechanism.脑源性神经营养因子通过新机制保护和修复多巴胺神经元。
Mol Psychiatry. 2022 Mar;27(3):1310-1321. doi: 10.1038/s41380-021-01394-6. Epub 2021 Dec 14.
5
Current status of ischemic stroke treatment: From thrombolysis to potential regenerative medicine.缺血性中风治疗的现状：从溶栓到潜在的再生医学。
Regen Ther. 2021 Oct 12;18:408-417. doi: 10.1016/j.reth.2021.09.009. eCollection 2021 Dec.
6
Platelets as drivers of ischemia/reperfusion injury after stroke.血小板在卒中后缺血/再灌注损伤中的作用。
Blood Adv. 2021 Mar 9;5(5):1576-1584. doi: 10.1182/bloodadvances.2020002888.
7
Decreased Expression of Cerebral Dopamine Neurotrophic Factor in Platelets of Stroke Patients.中风患者血小板中脑源性神经营养因子表达减少。
J Stroke Cerebrovasc Dis. 2020 Jan;29(1):104502. doi: 10.1016/j.jstrokecerebrovasdis.2019.104502. Epub 2019 Nov 16.
8
Cerebral Dopamine Neurotrophic Factor (CDNF) Has Neuroprotective Effects against Cerebral Ischemia That May Occur through the Endoplasmic Reticulum Stress Pathway.脑源性神经营养因子（CDNF）对可能通过内质网应激途径发生的脑缺血具有神经保护作用。
Int J Mol Sci. 2018 Jun 29;19(7):1905. doi: 10.3390/ijms19071905.
9
Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide.血红素加氧酶-1缺乏通过对内皮的氧化损伤加速动脉血栓形成，吸入一氧化碳可挽救这种损伤。
Circ Res. 2007 Oct 26;101(9):893-901. doi: 10.1161/CIRCRESAHA.107.158998. Epub 2007 Sep 20.
10
Rap1b is required for normal platelet function and hemostasis in mice.Rap1b对小鼠正常的血小板功能和止血作用是必需的。
J Clin Invest. 2005 Mar;115(3):680-7. doi: 10.1172/JCI22973.