Department of Clinical Research Management, Center of Biostatistics, Design, Measurement and Evaluation (CBDME), West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Sci Rep. 2024 Oct 26;14(1):25503. doi: 10.1038/s41598-024-76869-x.
Hypertension and high-normal blood pressure (BP) increase the risk for cardiovascular diseases. Examining trends in hypertension and high-normal BP among US adults is crucial. Participants aged 20 years or older from the 1999-2018 National Health and Nutrition Examination Surveys, were included. Trend analyses were performed to assess temporal changes in prevalence of hypertension and high-normal BP among US adults. Among the 48,580 participants included in this analysis, the mean (SD) age was 47.2 years (18 years) and 50.9% were women. Age-adjusted prevalence of hypertension was stable from 1999 to 2000 (29.5% [95% CI 26.6-32.3%]) through 2017-2018 (31.9%, [95% CI 29.0-34.7%]) (P = 0.265 for linear trend). Age-adjusted prevalence of high-normal BP decreased from 10.9% (95% CI 9.4-12.5%) in 1999-2000 to 8.0% (95% CI 7.1-9.0%) in 2007-2008, then increased to 9.8% (95% CI 8.3-11.3%) in 2017-2018 (P = 0.002 for nonlinear trend). Compared with men, hypertension and high-normal BP was less likely among women (multivariable-adjusted prevalence ratio, 0.90 [95% CI 0.84-0.97]; 0.68 [95% CI 0.52-0.88], respectively). Compared with non-Hispanic Black, high-normal BP was less likely among Mexican American, non-Hispanic White, and other race (multivariable-adjusted prevalence ratio, 0.59 [95% CI 0.44-0.79]; 0.53 [95% CI 0.41-0.69]; 0.56 [95% CI 0.74 - 0.71], respectively). The same held for hypertension.
高血压和正常高值血压(BP)会增加心血管疾病的风险。因此,检查美国成年人中高血压和正常高值血压的趋势至关重要。本研究纳入了年龄在 20 岁及以上的 1999-2018 年全国健康和营养检查调查参与者。采用趋势分析评估美国成年人中高血压和正常高值血压的流行率随时间的变化。在这项分析中,纳入了 48580 名参与者,平均(SD)年龄为 47.2 岁(18 岁),50.9%为女性。从 1999 年至 2000 年(29.5%[95%CI 26.6-32.3%])到 2017-2018 年(31.9%[95%CI 29.0-34.7%]),年龄校正后的高血压患病率保持稳定(P=0.265 线性趋势)。正常高值血压的年龄校正患病率从 1999-2000 年的 10.9%(95%CI 9.4-12.5%)下降到 2007-2008 年的 8.0%(95%CI 7.1-9.0%),然后在 2017-2018 年上升至 9.8%(95%CI 8.3-11.3%)(非线性趋势 P=0.002)。与男性相比,女性中高血压和正常高值血压的患病率较低(多变量校正后的患病率比,0.90[95%CI 0.84-0.97];0.68[95%CI 0.52-0.88])。与非西班牙裔黑人相比,墨西哥裔美国人、非西班牙裔白人以及其他种族的正常高值血压患病率较低(多变量校正后的患病率比,0.59[95%CI 0.44-0.79];0.53[95%CI 0.41-0.69];0.56[95%CI 0.74-0.71])。高血压也是如此。