İzmir City Hospital, Clinic of Ophthalmology, İzmir, Türkiye.
Turk J Ophthalmol. 2024 Oct 25;54(5):263-267. doi: 10.4274/tjo.galenos.2024.61094.
This study aimed to determine the frequency of epiretinal membrane (ERM) in the long term after neodymium-doped yttrium aluminum garnet laser iridotomy (LI) using spectral domain optical coherence tomography (SD-OCT).
This retrospective study included 94 eyes that underwent LI for primary angle-closure glaucoma, were followed for at least 4 years, and had no ERM before the procedure. The control group consisted of 66 eyes that were followed for suspected glaucoma did not have a previous ERM. We compared the ERM frequencies of the groups at the last visit. Additionally, ERM frequencies were compared between those who had cataract surgery in the post-LI period and those who did not.
After a follow-up period of at least 4 years, ERM developed in 36 of 94 eyes (38.2%) in the LI group. Of these, 32 were stage 1 ERM (34.0%) and 4 were stage 2 ERM (4.2%). In the control group, ERM developed in 13 of 66 eyes (19.6%), 12 of which were stage 1 ERM (18.1%) and 1 was stage 2 ERM (1.5%) (p=0.012). ERM developed in 14 of 32 eyes (43.7%) who underwent phacoemulsification surgery after LI and in 22 of 62 eyes (35.4%) that underwent only LI without subsequent cataract surgery (p=0.435). ERM developed significantly more frequently in the 62 phakic eyes that underwent only LI than in the eyes in the control group (p=0.045).
LI appears to be a predisposing factor for the development of ERM, regardless of subsequent cataract surgery.
本研究旨在通过频域光相干断层扫描（SD-OCT）确定钕钇铝石榴石激光虹膜切开术（LI）后长期发生后发性白内障膜（ERM）的频率。
本回顾性研究纳入了 94 例因原发性闭角型青光眼接受 LI 治疗的患者，这些患者的随访时间至少为 4 年，并且在手术前没有 ERM。对照组由 66 例因疑似青光眼而接受随访且无先前 ERM 的患者组成。我们比较了两组在最后一次就诊时的 ERM 频率。此外，还比较了 LI 后行白内障手术和未行白内障手术的患者的 ERM 频率。
LI 组 94 只眼中有 36 只（38.2%）在随访至少 4 年后出现 ERM，其中 32 只为 1 期 ERM（34.0%），4 只为 2 期 ERM（4.2%）。对照组 66 只眼中有 13 只（19.6%）出现 ERM，其中 12 只为 1 期 ERM（18.1%），1 只为 2 期 ERM（1.5%）（p=0.012）。LI 后行超声乳化白内障吸除术的 32 只眼中有 14 只（43.7%）出现 ERM，仅行 LI 且无后续白内障手术的 62 只眼中有 22 只（35.4%）出现 ERM（p=0.435）。仅行 LI 而未行后续白内障手术的 62 只未白内障眼发生 ERM 的频率明显高于对照组（p=0.045）。
LI 似乎是 ERM 发生的一个诱发因素，无论是否随后行白内障手术。
