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解读尿路结石:来自印度东部一家三级护理医院的成分见解与复发模式

Decoding Urinary Stones: Compositional Insights and Recurrence Patterns from a Tertiary Care Hospital in Eastern India.

作者信息

Kumar Prem, Ahmad Shamim, Prem Pranjal, Mazumdar Himangshu, Kiran Kumari Asha, Singh Smita

机构信息

Urology, Ranchi Urology Centre, Ranchi, IND.

Pathology and Laboratory Medicine, Dr Lal PathLabs, New Delhi, IND.

出版信息

Cureus. 2024 Sep 24;16(9):e70136. doi: 10.7759/cureus.70136. eCollection 2024 Sep.

Abstract

Background and objective Urinary stones are a prevalent medical condition entailing significant health burdens and substantial financial ramifications. Its global prevalence is expected to rise notably, particularly in low-middle-income nations. Understanding the spectrum of diverse urinary stone types is crucial for effective management and prevention. This study aims to elucidate the demographic profiles, clinical types, and recurrence of urinary stone cases at a tertiary care hospital in Eastern India. Methods and materials The clinical data from the electronic medical record of 1,231 patients with urolithiasis who underwent surgery in a tertiary care center in eastern India from January 2015 to November 2022 were retrospectively analyzed. Patient data, including demographic information, clinical records, dietary habits, water intake, and stone recurrence history, were collected. A thorough statistical analysis was conducted to elucidate the associations between patient characteristics, urinary stone composition, and recurrence. Results Among the 1,231 participants, the majority of cases (343 (27.9%)) were in the 31-40 age group, with a higher prevalence in males (876 (71.2%)) than in females (355 (28.8%)). Flank pain or abdominal pain (593 (48.1%)) was the primary complaint, followed by nausea/vomiting (227 (18.5%)). Most stones (922 (74.9%)) were located in the kidney, and calcium oxalate was the predominant stone component (773 (62.8%)). The highest stone recurrence rates were in patients aged between 21-30 years (21 (36.8%)) and 31-40 years (16 (28.0%)). A low non-vegetarian diet and adequate hydration may reduce the likelihood of stone recurrences. Conclusion This study provides insights into the compositional analysis of urinary stones in the eastern Indian population, addressing the causes of their recurrence and management strategies, which are crucial for prevention and effective management. The findings indicate that the early middle-aged group exhibited the highest incidence of urinary stones. We also observed that strict adherence to a low animal protein, along with proper hydration and lifestyle changes, significantly reduced urinary stone recurrence.

摘要

背景与目的

尿路结石是一种常见的疾病,带来了重大的健康负担和巨大的经济影响。预计其全球患病率将显著上升,尤其是在中低收入国家。了解各种尿路结石类型的范围对于有效管理和预防至关重要。本研究旨在阐明印度东部一家三级护理医院尿路结石病例的人口统计学特征、临床类型和复发情况。

方法与材料

回顾性分析了2015年1月至2022年11月在印度东部一家三级护理中心接受手术的1231例尿石症患者的电子病历中的临床数据。收集了患者数据,包括人口统计学信息、临床记录、饮食习惯、饮水量和结石复发史。进行了全面的统计分析,以阐明患者特征、尿路结石成分和复发之间的关联。

结果

在1231名参与者中,大多数病例(343例(27.9%))年龄在31-40岁之间,男性患病率(876例(71.2%))高于女性(355例(28.8%))。胁腹疼痛或腹痛(593例(48.1%))是主要症状,其次是恶心/呕吐(227例(18.5%))。大多数结石(922例(74.9%))位于肾脏,草酸钙是主要的结石成分(773例(62.8%))。结石复发率最高的是年龄在21-30岁(21例(36.8%))和31-40岁(16例(28.0%))的患者。低素食饮食和充足的水分摄入可能会降低结石复发的可能性。

结论

本研究为印度东部人群尿路结石的成分分析提供了见解,探讨了其复发原因和管理策略,这对于预防和有效管理至关重要。研究结果表明,中年早期人群尿路结石发病率最高。我们还观察到,严格坚持低动物蛋白饮食,同时适当补充水分和改变生活方式,可显著降低尿路结石复发率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c566/11502988/fb5e865643df/cureus-0016-00000070136-i01.jpg

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