Arvelaez Pascucci Joanne, Ghattas Patricia E, Olivas Lerma Ricardo, Villa Nogueyra Sol, Nogales Bernal María Belén, Milani Valentina, Floridia Rietmann Lautaro M, Alvarez Samantha M, Salaz Diaz Jorge
Infectious Disease, Universidad Central de Venezuela, Caracas, VEN.
Internal Medicine, Universidad Católica de Honduras, Tegucigalpa, HND.
Cureus. 2024 Sep 27;16(9):e70311. doi: 10.7759/cureus.70311. eCollection 2024 Sep.
Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide, highlighting the urgent need for effective prevention strategies. Emerging research suggests that the gut microbiome is critical in cardiovascular health, influencing pathophysiological processes associated with CVDs. This narrative review explores the intricate relationship between the gut microbiome and cardiovascular health, mainly focusing on how microbial composition affects inflammation, lipid metabolism, and endothelial function. Additionally, we discuss the implications of gut microbiome modulation through dietary interventions, prebiotics, and probiotics as potential therapeutic strategies for primary care practitioners. By emphasizing the importance of the microbiome in cardiovascular risk management, this review aims to inform primary care interventions that leverage microbiome research to improve patient outcomes and prevent CVDs. Ultimately, understanding and integrating gut health into cardiovascular care may provide a novel approach to enhancing cardiovascular resilience and reducing disease burden.
心血管疾病(CVDs)仍然是全球发病和死亡的主要原因,凸显了对有效预防策略的迫切需求。新兴研究表明,肠道微生物群对心血管健康至关重要,影响着与心血管疾病相关的病理生理过程。这篇叙述性综述探讨了肠道微生物群与心血管健康之间的复杂关系,主要关注微生物组成如何影响炎症、脂质代谢和内皮功能。此外,我们还讨论了通过饮食干预、益生元和益生菌调节肠道微生物群作为基层医疗从业者潜在治疗策略的意义。通过强调微生物群在心血管风险管理中的重要性,本综述旨在为基层医疗干预提供信息,这些干预利用微生物群研究来改善患者预后并预防心血管疾病。最终,理解并将肠道健康纳入心血管护理可能为增强心血管弹性和减轻疾病负担提供一种新方法。