Auerbach M, Haubenstock A, Soloman G
Am J Med. 1986 Feb;80(2):301-3. doi: 10.1016/0002-9343(86)90028-8.
Hemophagocytosis is a pathologic finding in a variety of infectious diseases associated with peripheral pancytopenia. In addition, hemophagocytosis is a prominent finding in malignant histiocytosis, a primary disorder of the monocyte-macrophage system. Systemic babesiosis is a rare parasitic disorder associated with intraerythrocytic parasites in the peripheral blood. There has been no description of the marrow findings in this disorder. A patient is described who had systemic babesiosis and prominent hemophagocytosis that disappeared after appropriate antiparasitic therapy. Systemic babesiosis should be considered in the differential diagnosis of hemophagocytosis.
噬血细胞现象是多种与外周血细胞减少相关的传染病中的一种病理表现。此外，噬血细胞现象在恶性组织细胞增多症（一种单核细胞 - 巨噬细胞系统的原发性疾病）中是一个突出表现。系统性巴贝斯虫病是一种罕见的寄生虫病，与外周血中的红细胞内寄生虫有关。目前尚无关于该疾病骨髓表现的描述。本文描述了一名患有系统性巴贝斯虫病且有明显噬血细胞现象的患者，经适当的抗寄生虫治疗后噬血细胞现象消失。在噬血细胞现象的鉴别诊断中应考虑系统性巴贝斯虫病。
