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广泛性焦虑障碍合并顽固性地图舌患者口干症状的改善及焦虑评分的降低:一例报告及文献综述

The Improvement of Xerostomia and Reduction of Anxiety Score in a Patient with Generalized Anxiety Disorder and Recalcitrant Geographic Tongue: A Case Report and Literature Review.

作者信息

Putri Nadia Tiara, Ridho Faiznur, Wahyuni Indah Suasani

机构信息

Oral Medicine Residency Program, Faculty of Dentistry, Universitas Padjadjaran, Bandung, West Java, Indonesia.

Oral Health Polyclinic, Oral Medicine Division, Dr. Rivai Abdullah Central General Hospital, Palembang, South Sumatera, Indonesia.

出版信息

Int Med Case Rep J. 2024 Oct 23;17:869-877. doi: 10.2147/IMCRJ.S480332. eCollection 2024.

DOI:10.2147/IMCRJ.S480332
PMID:39464490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11512784/
Abstract

INTRODUCTION

The incidence of post-pandemic psychiatric disorders has increased globally in recent decades. Generalized anxiety disorder (GAD) is one of the psychiatric disorders that are partially associated with emotional factors. It can affect the quantity and quality of saliva, present as xerostomia, and trigger the emergence of the geographic tongue (GT).

PURPOSE

This case report aims to discuss the management of xerostomia and geographic tongue in a patient with GAD.

CASE

A 26-year-old male patient complained of dry and sore mouth for one month after taking medication from the psychiatry department, was diagnosed with GAD, and had already consumed the antidepressant sertraline. Extraoral examination showed dry and exfoliative lips. Intraoral examination showed white plaque with depapilation on the dorsal tongue, frothy saliva, buccal mucosa and dorsal tongue sticking to the dental mirror. The unstimulated salivary flow rate was <0.2 mL/min (sialometry method). The Depression, Anxiety, and Stress Scale-21 (DASS-21) questionnaire was used to estimate the psychological condition and showed an extremely severe level of anxiety (score = 13). The established oral diagnoses were GT with mild xerostomia and exfoliative cheilitis.

CASE MANAGEMENT

For two months, patients received hyaluronic acid gel and mouthwash, as well as a non-pharmacological approach to healthy lifestyle counseling. There was an improvement in xerostomia, and the GT became asymptomatic, with a reduction of DASS score in this patient.

CONCLUSION

Improved psychological conditions will improve xerostomia, but the clinical appearance of the geographic tongue is more difficult to eliminate.

摘要

引言

近几十年来,全球大流行后精神障碍的发病率有所上升。广泛性焦虑症(GAD)是一种与情绪因素部分相关的精神障碍。它会影响唾液的量和质,表现为口干,并引发地图舌(GT)的出现。

目的

本病例报告旨在探讨广泛性焦虑症患者口干和地图舌的治疗。

病例

一名26岁男性患者在服用精神科药物一个月后出现口干和口腔疼痛,被诊断为广泛性焦虑症,且已服用抗抑郁药舍曲林。口外检查显示嘴唇干燥、脱屑。口内检查显示舌背有白色斑块伴乳头萎缩、唾液呈泡沫状、颊黏膜和舌背与口镜粘连。非刺激性唾液流速<0.2毫升/分钟(唾液测量法)。使用抑郁、焦虑和压力量表-21(DASS-21)问卷评估心理状况,结果显示焦虑程度极其严重(得分=13)。确诊的口腔疾病为轻度口干和脱屑性唇炎伴地图舌。

病例管理

两个月来,患者接受了透明质酸凝胶和漱口水治疗,以及健康生活方式咨询的非药物治疗方法。口干症状有所改善,地图舌无症状,该患者的DASS评分降低。

结论

心理状况的改善将改善口干,但地图舌的临床表现更难消除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2b/11512784/1c61a94a6b75/IMCRJ-17-869-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2b/11512784/1c01cd5609c7/IMCRJ-17-869-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2b/11512784/b38783e93c57/IMCRJ-17-869-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2b/11512784/b1f65429ed97/IMCRJ-17-869-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2b/11512784/1c61a94a6b75/IMCRJ-17-869-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2b/11512784/1c01cd5609c7/IMCRJ-17-869-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2b/11512784/b38783e93c57/IMCRJ-17-869-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2b/11512784/b1f65429ed97/IMCRJ-17-869-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f2b/11512784/1c61a94a6b75/IMCRJ-17-869-g0004.jpg

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本文引用的文献

1
Unveiling the Unspoken: Exploring Oral Manifestations of Psychological Disorders.揭示无言:探索心理障碍的口腔表现。
Cureus. 2024 Jan 25;16(1):e52967. doi: 10.7759/cureus.52967. eCollection 2024 Jan.
2
Xerostomia: From Pharmacological Treatments to Traditional Medicine-An Overview on the Possible Clinical Management and Prevention Using Systemic Approaches.口干症:从药物治疗到传统医学——全身性方法治疗和预防口干症的临床管理概述。
Curr Oncol. 2023 Apr 24;30(5):4412-4426. doi: 10.3390/curroncol30050336.
3
Effects of the COVID-19 pandemic on mental health, anxiety, and depression.
新冠疫情对心理健康、焦虑和抑郁的影响。
BMC Psychol. 2023 Apr 11;11(1):108. doi: 10.1186/s40359-023-01130-5.
4
Insight into the long-term psychological impacts of the COVID-19 pandemic.洞察2019冠状病毒病大流行的长期心理影响。
Eur Arch Psychiatry Clin Neurosci. 2023 Mar;273(2):287-288. doi: 10.1007/s00406-023-01599-6.
5
Stress as worsening of the signs and symptoms of the geographic tongue during the COVID-19 pandemic: a pilot study.压力会加重 COVID-19 大流行期间地图舌的体征和症状:一项初步研究。
BMC Oral Health. 2022 Dec 3;22(1):565. doi: 10.1186/s12903-022-02609-0.
6
COVID tongue.新冠舌
J Indian Soc Periodontol. 2022 Sep-Oct;26(5):498-500. doi: 10.4103/jisp.jisp_437_21. Epub 2022 Sep 1.
7
Depressive and Anxiety Symptoms in Severe COVID-19 Survivors: A Prospective Cohort Study.严重 COVID-19 幸存者的抑郁和焦虑症状:一项前瞻性队列研究。
Psychiatr Q. 2022 Sep;93(3):891-903. doi: 10.1007/s11126-022-09998-z. Epub 2022 Aug 10.
8
Oral Manifestations of Psychotropic Drugs on the Oral Cavity: Observational Study.精神药物对口腔的口腔表现:观察性研究。
J Contemp Dent Pract. 2022 Apr 1;23(4):443-446.
9
Reliability and validity of depression anxiety stress scale (DASS)-21 in screening for common mental disorders among postpartum women in Malawi.抑郁焦虑压力量表(DASS-21)在马拉维产后妇女常见精神障碍筛查中的信度和效度。
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10
Insight into the Role of Psychological Factors in Oral Mucosa Diseases.洞悉心理因素在口腔黏膜病中的作用。
Int J Mol Sci. 2022 Apr 26;23(9):4760. doi: 10.3390/ijms23094760.