Ekrampoor Mohammad Saleh, Daneste Hossein, Amiri Mohammad Amin
Department of Oral and Maxillofacial Surgery, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Galen Med J. 2023 Dec 17;12:e3144. doi: 10.31661/gmj.v12i.3144. eCollection 2023.
Calcifying epithelial odontogenic tumor (CEOT) and ameloblastoma are types of odontogenic tumors accounting for 1%, and 10% of all the odontogenic tumors. While sharing same odontogenic origin, these tumors are found to exhibit distinct clinicopathological features. In the present study, we present the third hybrid CEOT/Ameloblastoma tumor ever reported. The current CEOT/Amelobastoma is occurred after a previously operated CEOT in the same area. The patient was refered with distict clinical features of swelling and paresthesia. In the radiographic examination, a unilocular lesion with mixed internal structure and ambiguous periphery was seen which exhibited buccal and lingual cortical expansion, thining, and perforation as well as inferior alveolar canal perforation. The histopathology results suggested a CEOT/Ameloblastoma lesion. After the tumor removal, the patient was set up for further follow-ups and maxillofacial prosthesis.
牙源性钙化上皮瘤(CEOT)和成釉细胞瘤是牙源性肿瘤的两种类型,分别占所有牙源性肿瘤的1%和10%。虽然它们具有相同的牙源性起源,但这些肿瘤表现出不同的临床病理特征。在本研究中,我们报告了第三例混合性CEOT/成釉细胞瘤。目前的CEOT/成釉细胞瘤发生在同一区域先前手术切除的CEOT之后。患者因肿胀和感觉异常等明显临床特征前来就诊。在影像学检查中,可见一个内部结构混合且边界模糊的单房性病变,表现为颊侧和舌侧皮质膨胀、变薄和穿孔以及下牙槽神经管穿孔。组织病理学结果提示为CEOT/成釉细胞瘤病变。肿瘤切除后,安排患者进行进一步随访和颌面修复。