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上颌骨大型钙化上皮性牙源性肿瘤的手术治疗:一例报告。

Surgical management of a large calcifying epithelial odontogenic tumor in the maxilla: A case report.

作者信息

Gruber Kleber, de Freitas Filho Silas Antonio Juvencio, Dogenski Letícia Copatti, da Silva Bocassanta Ana Carolina, Paranhos Luiz Renato, de Carli João Paulo

机构信息

Department of Oral and Maxillofacial Surgery, Graduation in Dentistry, Paranaense University, Cascavel, PR, Brazil.

Post-Graduate Program in Applied Dental Sciences (Oral Pathology), Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.

出版信息

Int J Surg Case Rep. 2019;57:197-200. doi: 10.1016/j.ijscr.2019.03.055. Epub 2019 Apr 5.

Abstract

INTRODUCTION

The calcifying epithelial odontogenic tumor (CEOT), also known as Pindborg tumor, is a locally invasive benign neoplasm. Histogenesis is controversial.

PRESENTATION OF CASE

A 26-year-old male presented asymptomatic swelling on the right side of the face, with approximately six months of evolution. At intraoral examination, a hard nodule localized in the right posterior region of the maxilla, measuring approximately 5.0 x 3.0 cm was observed. The computed tomography images showed hypodense lesion with points of calcification associated with two non-erupted teeth. We suspect of odontogenic lesions. The final diagnosis of CEOT was established based on the histopathological aspects.

DISCUSSION

This tumor is more frequent in adult men, usually develops in the posterior region of the mandible and may present clinical-pathological similarities with others odontogenic lesions. The radiological aspects observed in the CEOT are variable and depend on the time of evolution of the tumor. The histopathological examination is mandatory to establish the final diagnosis.

CONCLUSION

Our case was treated with simple enucleation without signs of recurrence in five years of follow-up. Further studies are needed to understand the aetiology and the biological behaviour of this tumor.

摘要

引言

牙源性钙化上皮瘤(CEOT),也称为平博氏瘤,是一种局部侵袭性良性肿瘤。其组织发生存在争议。

病例介绍

一名26岁男性,右侧面部出现无症状肿胀,病程约6个月。口腔检查时,在上颌右侧后部发现一个硬结节,大小约为5.0×3.0厘米。计算机断层扫描图像显示低密度病变,伴有钙化点,与两颗未萌出的牙齿相关。我们怀疑是牙源性病变。根据组织病理学特征最终确诊为CEOT。

讨论

该肿瘤在成年男性中更为常见,通常发生在下颌后部,可能与其他牙源性病变存在临床病理相似性。CEOT的影像学表现多样,取决于肿瘤的发展时间。必须进行组织病理学检查以确立最终诊断。

结论

我们的病例采用简单摘除术治疗,随访五年无复发迹象。需要进一步研究以了解该肿瘤的病因和生物学行为。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be98/6463812/5754bf350fde/gr1.jpg

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