Yu Xinyi, Chen Qilan, Xu Lou Inmaculada
Department of Cardiology, Hangzhou TCM Hospital of Zhejiang Chinese Medical University (Hangzhou Hospital of Traditional Chinese Medicine), Hangzhou, China.
Front Nutr. 2024 Oct 11;11:1428010. doi: 10.3389/fnut.2024.1428010. eCollection 2024.
Heart failure (HF) is a syndrome of increased intracardiac pressure or decreased cardiac output. There is a lack of conclusive evidence to recommend the regular use of any dietary supplement in patients with HF. However, certain studies have shown nutritional interventions to be beneficial for patients with HF. Therefore, the purpose of this systematic review was to understand and map the updates of dietary interventions and nutritional supplementation measures related to patients with HF over the past 5 years.
A systematic review.
The PubMed, Web of Science, Scopus, and Cochrane Library databases were searched for randomized clinical trials on the association between dietary interventions and nutritional supplements and HF published between 2018 and 2023. A total of 1755 documents were retrieved, of which 19 were finalized for inclusion.
The findings suggest that individualized nutritional support reduces mortality and risk of major cardiovascular events in chronic heart failure inpatients at high nutritional risk. The Mediterranean diet improves functionality, quality of life, and cardiac function. Additionally, supplementation with thiamine, ubiquinol, D-ribose, and L-arginine enhances left ventricular ejection fraction. Probiotic yogurt may effectively improve the inflammatory and antioxidative status of chronic heart failure. Whey protein and melatonin have a positive effect on improving endothelial function in HF patients.
Certain dietary interventions and nutritional supplements may provide some benefit to patients with HF. However, there is no relevant definitive evidence on the impact of nutritional interventions on the prognosis of HF, and more high-quality clinical trials are needed for further in-depth studies.
Identifier, CRD42024510847.
心力衰竭（HF）是一种心内压升高或心输出量降低的综合征。目前缺乏确凿证据推荐在HF患者中常规使用任何膳食补充剂。然而，某些研究表明营养干预对HF患者有益。因此，本系统评价的目的是了解并梳理过去5年中与HF患者相关的饮食干预和营养补充措施的最新情况。
系统评价。
在PubMed、科学网、Scopus和Cochrane图书馆数据库中检索2018年至2023年间发表的关于饮食干预、营养补充剂与HF之间关联的随机临床试验。共检索到1755篇文献，其中19篇最终确定纳入。
研究结果表明，个体化营养支持可降低高营养风险的慢性心力衰竭住院患者的死亡率和主要心血管事件风险。地中海饮食可改善身体功能、生活质量和心脏功能。此外，补充硫胺素、泛醇、D-核糖和L-精氨酸可提高左心室射血分数。益生菌酸奶可有效改善慢性心力衰竭的炎症和抗氧化状态。乳清蛋白和褪黑素对改善HF患者的内皮功能有积极作用。
某些饮食干预和营养补充剂可能对HF患者有益。然而，关于营养干预对HF预后影响的相关确凿证据不足，需要更多高质量的临床试验进行进一步深入研究。
标识符，CRD42024510847。
