Carmichael J A, Clarke D H, Moher D, Ohlke I D, Karchmar E J
Am J Obstet Gynecol. 1986 Feb;154(2):264-9. doi: 10.1016/0002-9378(86)90652-6.
This presentation addresses three questions concerning invasive cervical carcinoma in women 34 years of age and younger. Is there an increase in the incidence of the disease? Is it more or less susceptible to prevention by cervical screening? Is the clinical behavior different for this age group? Three separate studies are reported: (1) Incidence data in the younger age group have been reviewed at the national, provincial, and local levels. (2) Cytologic screening histories of 125 patients who subsequently developed cervical carcinoma were reviewed. (3) The clinical histories of 121 women 34 years of age and younger, with invasive cervical carcinoma, were reviewed and compared with those of 242 control women 35 years of age and older. Results indicate an increase in incidence in the younger age groups in the three prairie provinces only. Cytologic histories are similar except for an increase in false negative reports in the younger age group. Clinical behavior of the disease is similar for both age groups.
本报告探讨了三个与34岁及以下女性浸润性宫颈癌有关的问题。该疾病的发病率是否上升？它对宫颈筛查预防的易感性是更高还是更低？这个年龄组的临床行为是否不同？报告了三项独立研究：（1）在国家、省级和地方层面审查了较年轻年龄组的发病率数据。（2）回顾了125例随后患宫颈癌患者的细胞学筛查史。（3）回顾了121例34岁及以下浸润性宫颈癌女性的临床病史，并与242例35岁及以上对照女性的临床病史进行了比较。结果表明，仅在三个草原省份，较年轻年龄组的发病率有所上升。除较年轻年龄组假阴性报告增加外，细胞学筛查史相似。两个年龄组该疾病的临床行为相似。
