Totsuka-ekimae Suzuki Eye Clinic, Yokohama, Japan.
Department of Ophthalmology, Tokyo Dental College Suidobashi Hospital, 2-9-18 KandaMisaki-cho, Chiyoda-ku, Tokyo, 101-0061, Japan.
BMC Ophthalmol. 2024 Oct 28;24(1):469. doi: 10.1186/s12886-024-03735-9.
To prospectively evaluate binocular visual outcomes after implantation of trifocal intraocular lenses (IOLs) with high-water-content hydrophobic acrylic material in Japanese patients.
In 59 patients (mean age 65.1 ± 7.9 years), Clareon PanOptix (CNWTT0: Alcon) with a high-water-content hydrophobic acrylic material was implanted bilaterally. Three months postoperatively, binocular uncorrected visual acuity (BUCVA) and distance-corrected visual acuity (BDCVA) at distances of 5 m, 80, 60, and 40 cm, binocular defocus curves, and binocular photopic contrast sensitivity were examined. Subjective symptoms (night vision disturbance, glare, halos, haze, or blurry vision) were also assessed.
The mean postoperative BUCVA/BDCVA at 5 m, 80 cm, 60 cm, and 40 cm were - 0.115/-0.163, -0.052/-0.047, -0.054/-0.075, and - 0.043/-0.067 logMAR, respectively. A smooth defocus curve, contrast sensitivity within the normal range, and acceptable subjective symptom rates were obtained.
The trifocal IOL, composed of a high-water-content hydrophobic acrylic material, provides good continuous binocular vision from distance to near.
This investigator-initiated study was registered in the Japan Registry for Clinical Trials (identifier: jRCTs032220042) on April 26, 2022.
前瞻性评估日本患者植入高含水量疏水性丙烯酸材料的三焦点人工晶状体（IOL）后的双眼视觉效果。
在 59 名患者（平均年龄 65.1±7.9 岁）中，双侧植入 Clareon PanOptix（CNWTT0：Alcon），这是一种高含水量疏水性丙烯酸材料。术后 3 个月，检查双眼未矫正视力（BUCVA）和远距矫正视力（BDCVA），距离为 5m、80、60 和 40cm，双眼离焦曲线和双眼明视对比敏感度。还评估了主观症状（夜间视力障碍、眩光、晕影、模糊或视力模糊）。
5m、80cm、60cm 和 40cm 时平均术后 BUCVA/BDCVA 分别为-0.115/-0.163、-0.052/-0.047、-0.054/-0.075 和-0.043/-0.067 logMAR。获得了平稳的离焦曲线、在正常范围内的对比敏感度和可接受的主观症状发生率。
由高含水量疏水性丙烯酸材料组成的三焦点 IOL 可提供从远距到近距的良好连续双眼视觉。
这项由研究者发起的研究于 2022 年 4 月 26 日在日本临床试验注册处（标识符：jRCTs032220042）注册。
