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血液中铅含量高和低的儿童生物特征数据比较。

Comparison of biometric data of children with high and low levels of lead in the blood.

作者信息

Lauwers M C, Hauspie R C, Susanne C, Verheyden J

出版信息

Am J Phys Anthropol. 1986 Jan;69(1):107-16. doi: 10.1002/ajpa.1330690112.

Abstract

This paper deals with a biometric study of 312 boys and girls, aged 2.5-16 years, living in an area with a long history of pollution by lead. The aim was to search for eventual relationships between ten biometric variables and measures of lead absorption in the bodies, i.e. the amount of lead in the blood (PbB), of these children. Standardized values of the biometric variables were compared in the high-PbB and low-PbB categories, by multivariate analysis of variance. Comparison of the vectors of the ten biometric variables reveals a significant difference between the two categories of PbB levels. We found some evidence that the younger children (below 8 years of age) are more likely to absorb lead in the body and are more vulnerable to the effects of subclinical lead intoxication than their older counterparts. The differences between the averages of biometric variables in the two PbB categories are consistently (although not significantly) greater among younger children. This trend disappeared in the older age group. These results confirm data from the literature that young children are especially at risk. It can be concluded that there is a subtle, but significant, influence of lead absorption on the biometric profiles of children and that this effect is probably more important in children below 8 years of age.

摘要

本文对居住在一个有长期铅污染历史地区的312名年龄在2.5至16岁的男孩和女孩进行了生物特征研究。目的是探寻这10项生物特征变量与这些儿童体内铅吸收量(即血铅含量,PbB)之间可能存在的关系。通过多变量方差分析,比较了高血铅组和低血铅组生物特征变量的标准化值。对这10项生物特征变量的向量进行比较,发现两组血铅水平之间存在显著差异。我们发现一些证据表明,年幼的儿童(8岁以下)比年龄较大的儿童更有可能在体内吸收铅,并且更容易受到亚临床铅中毒影响。在两个血铅组中,生物特征变量平均值之间的差异在年幼儿童中始终(尽管不显著)更大。在年龄较大的组中,这种趋势消失了。这些结果证实了文献中的数据,即幼儿尤其面临风险。可以得出结论,铅吸收对儿童的生物特征概况有微妙但显著的影响,并且这种影响在8岁以下儿童中可能更为重要。

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