Departments of Dermatology and Pathology, Penn State Hershey Medical Center, 500 University Drive Box 850/ HU-14, Hershey, PA, 17033, USA.
University of Virginia Health System, Charlottesville, VA, USA.
Head Neck Pathol. 2024 Oct 28;18(1):115. doi: 10.1007/s12105-024-01718-2.
Eosinophils are often encountered in the stroma and peritumoral microenvironment of squamous cell carcinomas. Because eosinophils are readily identified on routine hematoxylin and eosin stained sections, researchers have explored multiple ways in which identifying the extent of eosinophil infiltration on routine biopsy and excisional specimens might provide diagnostic and prognostic information. We review the literature on this evolving topic.
嗜酸性粒细胞通常存在于鳞状细胞癌的基质和肿瘤周围微环境中。由于嗜酸性粒细胞在常规苏木精和伊红染色切片中易于识别,因此研究人员已经探索了多种方法,试图通过常规活检和切除标本来识别嗜酸性粒细胞浸润的程度,以期提供诊断和预后信息。我们对这一不断发展的主题的文献进行了回顾。