Marcy Daniele, Zell JoAnn, Demoruelle M Kristen
Division of Rheumatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Semin Reprod Med. 2024 Sep;42(3):169-177. doi: 10.1055/s-0044-1790255. Epub 2024 Oct 28.
Rheumatoid arthritis (RA) is a systemic autoimmune disease that more commonly affects women, including many women during the childbearing years. This can make management challenging for practitioners involved in the care of these patients. This review article will discuss the available data and expert recommendations pertaining to women with RA who are pregnant or planning pregnancy. Herein, we will consider pregnancy complications associated with RA, the benefits of maintaining low disease activity prior to conception and throughout pregnancy, flare management during pregnancy, ensuring pregnancy-compatible medications to treat RA, and the reduced rates of fertility in patients with RA. While research in this area has greatly expanded over the past decade, it continues to be an area where more research is needed to best support women with RA as they navigate pregnancy.
类风湿性关节炎(RA)是一种全身性自身免疫性疾病,女性更为常见,包括许多育龄期女性。这给参与这些患者护理的从业者带来了管理挑战。这篇综述文章将讨论与怀孕或计划怀孕的类风湿性关节炎女性相关的现有数据和专家建议。在此,我们将考虑与类风湿性关节炎相关的妊娠并发症、受孕前及整个孕期维持低疾病活动度的益处、孕期病情复发的管理、确保使用适合孕期治疗类风湿性关节炎的药物,以及类风湿性关节炎患者生育率降低的情况。虽然该领域的研究在过去十年有了很大扩展,但在这个领域仍需要更多研究,以便在类风湿性关节炎女性应对妊娠时提供最佳支持。