School of Chemical, Biological and Battery Engineering, Gachon University, 1342 Seongnam-daero, Seongnam-si, Gyeonggi-do 13120, Republic of Korea.
AMOREPACIFIC R&I Center, 1920 Yonggu-daero, Yongin-si, Gyeonggi-do 17074, Republic of Korea.
Biomater Sci. 2024 Nov 19;12(23):6136-6147. doi: 10.1039/d4bm01254b.
The cosmetics industry is increasingly focusing on developing sustainable and environmentally friendly products while maintaining high performance. In color cosmetics, achieving long-lasting durability of water-soluble dyes remains a challenge. This study presents a sustainable approach to enhance the durability of water-soluble dyes in cosmetics using biopolymer-based films. The casein films were fabricated through riboflavin phosphate (RFP)-mediated photo-crosslinking, with tannic acid (TA) incorporated to improve mechanical properties. The fabrication process, characterization, and performance evaluation of the biopolymer-based films were investigated. Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) analyses confirmed the successful crosslinking and formation of a porous network structure. Rheological measurements revealed that the incorporation of TA significantly enhanced the mechanical strength of the films. Cytocompatibility assessment using NIH/3T3 fibroblasts demonstrated the films' excellent biocompatibility. The durability and color retention of a water-soluble red dye in the biopolymer-based films were evaluated on human skin. The films formed under blue light irradiation exhibited superior dye retention compared to non-irradiated films, with TA addition providing a minor improvement in durability. This study bridges the gap between cosmetic science and biomaterials research, providing a foundation for future investigations into bio-interactive materials for dermal applications. These findings highlight the potential of RFP-mediated photo-crosslinked casein films as a sustainable and effective solution for enhancing the durability of water-soluble dyes in color cosmetics.
化妆品行业越来越注重开发可持续和环保的产品，同时保持高性能。在彩妆产品中，水溶性染料的长效耐久性仍然是一个挑战。本研究提出了一种使用基于生物聚合物的薄膜来提高化妆品中水溶性染料耐久性的可持续方法。通过核黄素磷酸盐（RFP）介导的光交联制备酪蛋白薄膜，并加入单宁酸（TA）以改善机械性能。研究了基于生物聚合物的薄膜的制造工艺、表征和性能评估。傅里叶变换红外光谱（FTIR）和扫描电子显微镜（SEM）分析证实了成功的交联和多孔网络结构的形成。流变学测量表明，TA 的加入显著提高了薄膜的机械强度。使用 NIH/3T3 成纤维细胞进行的细胞相容性评估表明，薄膜具有优异的生物相容性。在人体皮肤上评估了水溶性红色染料在基于生物聚合物的薄膜中的耐久性和颜色保留。在蓝光照射下形成的薄膜与未照射的薄膜相比，表现出更好的染料保留性，而 TA 的加入对耐久性略有改善。本研究弥合了化妆品科学和生物材料研究之间的差距，为未来用于皮肤应用的生物相互作用材料的研究提供了基础。这些发现突出了 RFP 介导的光交联酪蛋白薄膜作为提高彩妆中水溶性染料耐久性的可持续有效解决方案的潜力。
