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生长激素对大鼠鼻中隔生长的影响。

Influence of growth hormone on nasal septal growth in rats.

作者信息

Vetter U, Heinze E, Voigt K H, Pirsig W

出版信息

Ann Otol Rhinol Laryngol. 1986 Jan-Feb;95(1 Pt 1):91-3. doi: 10.1177/000348948609500119.

DOI:10.1177/000348948609500119
PMID:3947008
Abstract

Growth activity of the rat septal cartilage was evaluated by incorporating radiolabeled sulfate into three areas of the septal cartilage (anterior, central, and posterior). Growth activity of the septal cartilage was determined in normal rats and in hypophysectomized rats treated either with saline or human growth hormone (hGh) injections. Human growth hormone treatment selectively stimulated sulfate incorporation in the posterior area, which is situated anterior to the septoethmoidal junction, whereas sulfate incorporation was not influenced in the anterior and central area by hGh treatment compared to saline treatment. However, both wet and dry weight was significantly increased by hGh treatment compared to saline treatment in hypophysectomized rats.

摘要

通过将放射性标记的硫酸盐掺入鼻中隔软骨的三个区域(前部、中部和后部)来评估大鼠鼻中隔软骨的生长活性。在正常大鼠以及接受生理盐水或人生长激素(hGh)注射治疗的垂体切除大鼠中测定鼻中隔软骨的生长活性。人生长激素治疗选择性地刺激了位于筛骨鼻中隔交界处前方的后部区域的硫酸盐掺入,而与生理盐水治疗相比,人生长激素治疗对前部和中部区域的硫酸盐掺入没有影响。然而,与生理盐水治疗相比,人生长激素治疗使垂体切除大鼠的湿重和干重均显著增加。

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1
Influence of growth hormone on nasal septal growth in rats.生长激素对大鼠鼻中隔生长的影响。
Ann Otol Rhinol Laryngol. 1986 Jan-Feb;95(1 Pt 1):91-3. doi: 10.1177/000348948609500119.
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