Kim Seung J J, Kim Sangwan, Cho Ara, Han Ahram, Ha Jongwon, Min Sangil
Department of Surgery, Seoul National University College of Medicine.
Institute of Health Policy and Management, Seoul National University Medical Research Center.
Int J Surg. 2024 Nov 1;110(11):7121-7133. doi: 10.1097/JS9.0000000000002019.
Kidney transplantation is the preferred treatment for patients with end-stage kidney disease. Since the introduction of robot-assisted kidney transplantation (RAKT), several centers have applied this technique as an alternative to open kidney transplantation (OKT). The objective of this study is to analyze our early experience, focusing on surgical technique and learning curve, and postoperative outcomes of RAKT.
The authors retrospectively reviewed 782 living donor kidney transplantation recipients between January 2018 and January 2024. A propensity score-matched cohort of 50 RAKT and 150 OKT patients was evaluated for intraoperative and postoperative variables. Shewhart control charts and CUSUM analysis were used to evaluate the technical outcomes and learning curves of RAKT. Postoperative eGFR values, complications, and biopsy results were compared for overall graft function and safety.
RAKT patients were associated with significantly longer overall operative, rewarming, and anastomosis times. Although overall postoperative eGFR trends showed comparable graft function between RAKT and OKT recipients (51.35±2.64 vs. 54.01±1.45; P =0.315), RAKT patients with extremely long rewarming times exhibited aggravated chronic scores at 1-year protocol biopsies (Δ Chronicity Index=4.45±1.92, P <0.001). CUSUM analysis of rewarming time revealed that proficiency in RAKT is achieved after ~15 cases.
Despite longer anastomosis and ischemic times, even during the early stages of RAKT adoption, the RAKT group did not differ significantly in graft function or postoperative complications from the OKT group.
肾移植是终末期肾病患者的首选治疗方法。自从引入机器人辅助肾移植(RAKT)以来,多个中心已将该技术作为开放性肾移植(OKT)的替代方法应用。本研究的目的是分析我们的早期经验,重点关注手术技术、学习曲线以及RAKT的术后结果。
作者回顾性分析了2018年1月至2024年1月期间782例活体供肾肾移植受者。对50例RAKT患者和150例OKT患者的倾向评分匹配队列进行术中及术后变量评估。使用休哈特控制图和累积和分析来评估RAKT的技术结果和学习曲线。比较术后估算肾小球滤过率(eGFR)值、并发症及活检结果,以评估总体移植肾功能和安全性。
RAKT患者的总体手术时间、复温时间和吻合时间明显更长。尽管总体术后eGFR趋势显示RAKT和OKT受者之间的移植肾功能相当(51.35±2.64 vs. 54.01±1.45;P = 0.315),但复温时间极长的RAKT患者在1年方案活检时慢性评分加重(慢性指数变化=4.45±1.92,P <0.001)。复温时间的累积和分析显示,约15例手术后可达到RAKT熟练程度。
尽管吻合时间和缺血时间更长,但即使在采用RAKT的早期阶段,RAKT组与OKT组在移植肾功能或术后并发症方面也没有显著差异。