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急性呼吸衰竭中膈肌运动的视觉模式:一项前瞻性初步研究。

Visual Patterns of Diaphragmatic Motion in Acute Respiratory Failure: A Prospective Pilot Study.

作者信息

Markarian Thibaut, Daniel Matthieu, Guillemet Kevin, Ajavon Florian, Femy Florent, Grandpierre Romain Genre, Feral-Pierssens Anne-Laure, Bobbia Xavier

机构信息

Department of Emergency Medicine, Assistance publique des hôpitaux de Marseille (APHM), Timone University Hospital, Aix-Marseille University, UMR 1263 (C2VN), Marseille, France.

Department of Emergency Medicine SAMU-SMUR 974, La Réunion University Hospital, University of La Réunion, Saint-Denis de La Réunion, France.

出版信息

J Clin Ultrasound. 2025 Mar-Apr;53(3):421-428. doi: 10.1002/jcu.23886. Epub 2024 Oct 29.

Abstract

INTRODUCTION

Right diaphragmatic excursion is a reliable and reproducible technique used in intensive care to assess diaphragmatic function. The aim of this study was to investigate the relationship between the appearance of diaphragmatic motion and the etiological diagnosis of patients admitted to the emergency department with acute respiratory failure (ARF).

MATERIALS

A prospective, observational, and multicenter pilot study was conducted. All adult patients admitted in the emergency department with ARF were included. The different visual patterns of diaphragmatic motion were analyzed according to the three main etiologies of ARF encountered in emergency departments.

RESULTS

A total of 39 adult patients were included. We observed a different visual pattern in patients with pneumonia. A sum of plateau times of less than 0.2 s predicted that the main diagnosis was pneumonia, with sensitivity = 89% 95%CI [52%; 100%], specificity = 87% 95%CI [69%; 96%].

CONCLUSION

Our study seems to show that the shape of diaphragmatic motion in patients with ARF secondary to pneumonia is different from that in patients with exacerbation of chronic obstructive pulmonary disease or acute heart failure.

TRIAL REGISTRATION

ClinicalTrials.gov: NCT04591509.

摘要

引言

右侧膈肌活动度是重症监护中用于评估膈肌功能的一种可靠且可重复的技术。本研究的目的是调查急性呼吸衰竭(ARF)患者膈肌运动表现与病因诊断之间的关系。

材料

进行了一项前瞻性、观察性多中心试点研究。纳入所有因急性呼吸衰竭入住急诊科的成年患者。根据急诊科遇到的急性呼吸衰竭的三种主要病因,分析膈肌运动的不同视觉模式。

结果

共纳入39例成年患者。我们在肺炎患者中观察到了不同的视觉模式。平台期总时长小于0.2秒预测主要诊断为肺炎,敏感性=89% 95%CI[52%;100%],特异性=87% 95%CI[69%;96%]。

结论

我们的研究似乎表明,肺炎继发急性呼吸衰竭患者的膈肌运动形态与慢性阻塞性肺疾病加重或急性心力衰竭患者不同。

试验注册

ClinicalTrials.gov:NCT04591509。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e30/11907226/a13f57535104/JCU-53-421-g004.jpg

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