Faculty of Nursing, Al-Balqa Applied University, Salt, Jordan.
Acute and Critical Care, University of Jordan, Amman, Jordan.
Medicine (Baltimore). 2024 Oct 25;103(43):e40169. doi: 10.1097/MD.0000000000040169.
The aim of this study was to describe the 30-day mortality rate of adult patients with sepsis and septic shock in 6 intensive care units of 2 tertiary hospitals in Jordan. A prospective cohort design was used. Patients with sepsis and septic shock admitted to the medical and surgical intensive care units at 2 tertiary hospitals were followed up during the period between February 2022 and June 2022 (N = 148). Data were analyzed using SPSS, version 23. Moreover, descriptive statistics, chi-square, and binary logistic regression were used. Notably, 52.7% of patients with sepsis and septic shock died within 30 days of diagnosis of sepsis and septic shock. Sequential Organ Failure Assessment score and the history of having solid tumors significantly predicted the 30-day mortality rate. Moreover, 43 (29.0%) patients with sepsis and septic shock had positive blood cultures, and 46 (31.0%) had positive urine cultures. Patients with sepsis and septic shock have a notable mortality rate that can be predicted from total Sequential Organ Failure Assessment scores and from the history of having solid tumors. Early assessment and initiation of treatment for sepsis essentially would reduce the likelihood of progression of sepsis to septic shock and would reduce associated patients' mortality.
本研究旨在描述约旦 2 家 3 级医院 6 个重症监护病房中成年脓毒症和脓毒性休克患者的 30 天死亡率。采用前瞻性队列设计。在 2022 年 2 月至 6 月期间，对 2 家 3 级医院的内科和外科重症监护病房收治的脓毒症和脓毒性休克患者进行了随访（N=148）。使用 SPSS 版本 23 对数据进行分析。此外，还使用了描述性统计、卡方检验和二元逻辑回归。值得注意的是，52.7%的脓毒症和脓毒性休克患者在诊断为脓毒症和脓毒性休克后的 30 天内死亡。序贯器官衰竭评估评分和患有实体肿瘤的病史显著预测了 30 天死亡率。此外，43（29.0%）例脓毒症和脓毒性休克患者的血培养阳性，46（31.0%）例患者的尿培养阳性。脓毒症和脓毒性休克患者的死亡率相当高，可通过总序贯器官衰竭评估评分和患有实体肿瘤的病史来预测。早期评估和开始治疗脓毒症可以降低脓毒症进展为脓毒性休克的可能性，并降低相关患者的死亡率。
