All India Institute of Medical Sciences, Bhubaneswar, India.
Department of Medical-Surgical Nursing, Manipal College of Nursing Manipal Academy of Higher Education, Karnataka, India.
Asian Pac J Cancer Prev. 2024 Oct 1;25(10):3421-3428. doi: 10.31557/APJCP.2024.25.10.3421.
Nausea and vomiting are one of the common and distressing side effects of chemotherapy in breast cancer patients often impacting their quality of life and treatment adherence. The purpose of this systematic review and meta-analysis was to determine whether acupressure is effective in treating breast cancer patients' acute nausea and vomiting brought on by chemotherapy as well as delayed nausea and vomiting.
We systematically searched for Randomized controlled trials and quasi-experimental studies in PubMed, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Clinical Key, Web of Science, EMBASE, and Scopus. Based on the inclusion criteria two reviewers independently identified the articles using key thesaurus and free text terms. The review was guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement.
According to the pooled findings, acupressure combined with antiemetics greatly lessens the severity of acute nausea [SMD, (95% CI)] [-0.35(-0.62,-0.08), P=0.01, I2=0%], delayed nausea [SMD, (95% CI)] [-0.52(-0.78,-0.26), P<0.001, I2=16%], and delayed vomiting [SMD, (95% CI)] [-0.46(- 0.83,-0.08), P=0.02, I2=43%] brought on by chemotherapy.
For chemotherapy-treated breast cancer patients, acupressure is a helpful complementary therapy for easing nausea and vomiting.
恶心和呕吐是乳腺癌患者化疗中常见且令人痛苦的副作用之一,常影响其生活质量和治疗依从性。本系统评价和荟萃分析的目的是确定按压穴位是否能有效治疗乳腺癌患者化疗引起的急性恶心和呕吐,以及延迟性恶心和呕吐。
我们系统地检索了 PubMed、Cochrane 中央对照试验注册库、护理学及相关健康文献累积索引(CINAHL)、ClinicalKey、Web of Science、EMBASE 和 Scopus 中的随机对照试验和准实验研究。根据纳入标准,两名评审员使用主题词和自由文本词独立识别文章。本综述遵循系统评价和荟萃分析的首选报告项目(PRISMA)声明。
根据汇总结果,穴位按压联合止吐药可显著减轻急性恶心的严重程度[SMD,(95%CI)](-0.35[-0.62,-0.08),P=0.01,I2=0%)]、延迟性恶心[SMD,(95%CI)](-0.52[-0.78,-0.26),P<0.001,I2=16%)]和化疗引起的延迟性呕吐[SMD,(95%CI)](-0.46[-0.83,-0.08),P=0.02,I2=43%)]。
对于接受化疗的乳腺癌患者,穴位按压是一种缓解恶心和呕吐的有益辅助疗法。