Community Health Campaign Bharatpur, Nepal.
Early Detection, Prevention and Infection Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France.
Asian Pac J Cancer Prev. 2024 Oct 1;25(10):3635-3642. doi: 10.31557/APJCP.2024.25.10.3635.
In Nepal, gastric cancer was the second most common cause of cancer deaths in males and the fifth most common cause of cancer deaths in females in 2020. Although gastric cancer is a significant public health problem, there have been no studies undertaken in Nepal to determine the survival and predictors of gastric cancer survival.
A retrospective cohort study of gastric cancer patients at Bhaktapur Cancer Hospital in Kathmandu Valley, Nepal. Data were analysed from 817 new gastric cancer cases, diagnosed between January 2010 and December 2021. Survival rate was analyzed using Kaplan-Meyer methods, and predictors of gastric cancer survival were analyzed using Cox Regression methods.
The median overall survival for gastric cancer patients was 19 months since diagnosis. The five-year survival rate was 12%. The predictors for survival were younger age, tumors located in the non-cardia, early stage, treatment by surgery, and treatment by chemotherapy. However, sex, histologic type, tumor grade, tumor subtype, and extent of cancer were not associated with survival.
In Nepal, the overall survival of patients with gastric cancer was 12%, which is much lower than in high-income countries. Predictors of survival were patient age at diagnosis, the stage at diagnosis, the location of the tumor, and the treatment undertaken, both in Nepal and in high-income countries.
在尼泊尔，2020 年胃癌是男性癌症死亡的第二大主要原因，也是女性癌症死亡的第五大主要原因。尽管胃癌是一个重大的公共卫生问题，但尼泊尔尚未开展任何研究来确定胃癌的生存率和生存预测因素。
这是一项在尼泊尔加德满都山谷巴克拉普尔癌症医院进行的胃癌患者回顾性队列研究。分析了 2010 年 1 月至 2021 年 12 月期间诊断的 817 例新胃癌病例的数据。使用 Kaplan-Meier 方法分析生存率，使用 Cox 回归方法分析胃癌生存的预测因素。
胃癌患者的中位总生存期为诊断后 19 个月。五年生存率为 12%。生存的预测因素是年龄较小、肿瘤位于非贲门、早期、手术治疗和化疗治疗。然而，性别、组织学类型、肿瘤分级、肿瘤亚型和癌症程度与生存无关。
在尼泊尔，胃癌患者的总体生存率为 12%，远低于高收入国家。生存的预测因素包括诊断时的患者年龄、诊断时的分期、肿瘤的位置以及在尼泊尔和高收入国家都进行的治疗。
