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Antiviral activity of lipoxygenase against severe fever with thrombocytopenia syndrome virus.

作者信息

Li Shuang, Zheng Xiaojie, Zhang Yunfa, Zhang Lingyu, Yang Tong, Li Hao, Zhou Caiyu, Zhang Xiao-Ai, Gao Li-Zeng, Liu Wei

机构信息

Department of Infectious Disease Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science, Beijing 100071, China.

Department of Research and Development, Luoyang TMAXTREE Biotechnology Co., Ltd., Luoyang 471000, China.

出版信息

Protein Cell. 2025 Feb 1;16(2):143-147. doi: 10.1093/procel/pwae061.

DOI:10.1093/procel/pwae061
PMID:39471353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11786719/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dedf/11786719/7c213774b164/pwae061_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dedf/11786719/443a77f8f0c5/pwae061_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dedf/11786719/7c213774b164/pwae061_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dedf/11786719/443a77f8f0c5/pwae061_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dedf/11786719/7c213774b164/pwae061_fig2.jpg

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本文引用的文献

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Sci Adv. 2023 Aug 2;9(31):eadg6856. doi: 10.1126/sciadv.adg6856.
2
Daidzein phosphorylates and activates 5-lipoxygenase via the MEK/ERK pathway: a mechanism for inducing the production of 5-lipoxygenase metabolite that inhibit influenza virus intracellular replication.大豆苷元通过MEK/ERK途径使5-脂氧合酶磷酸化并激活：一种诱导产生抑制流感病毒细胞内复制的5-脂氧合酶代谢产物的机制。
J Nutr Biochem. 2023 Apr;114:109276. doi: 10.1016/j.jnutbio.2023.109276. Epub 2023 Jan 20.
3
Bacterial lipoxygenases: Biochemical characteristics, molecular structure and potential applications.
细菌脂氧合酶：生化特性、分子结构及潜在应用。
Biotechnol Adv. 2022 Dec;61:108046. doi: 10.1016/j.biotechadv.2022.108046. Epub 2022 Oct 4.
4
In Silico Structure-Based Design of Antiviral Peptides Targeting the Severe Fever with Thrombocytopenia Syndrome Virus Glycoprotein Gn.基于结构的抗病毒肽的计算机设计，针对发热伴血小板减少综合征病毒糖蛋白 Gn。
Viruses. 2021 Oct 11;13(10):2047. doi: 10.3390/v13102047.
5
Catalytic inactivation of influenza virus by iron oxide nanozyme.氧化铁纳米酶催化失活流感病毒。
Theranostics. 2019 Sep 21;9(23):6920-6935. doi: 10.7150/thno.35826. eCollection 2019.
6
The role of lipoxygenases in pathophysiology; new insights and future perspectives.脂氧合酶在病理生理学中的作用；新见解与未来展望。
Redox Biol. 2015 Dec;6:297-310. doi: 10.1016/j.redox.2015.08.006. Epub 2015 Aug 7.
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