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开放手术与腹腔镜手术及机器人辅助腹股沟疝修补术:倾向评分匹配的结果分析。

Open versus laparoscopic versus robotic inguinal hernia repair: A propensity-matched outcome analysis.

作者信息

Lorenz William R, Holland Alexis M, Adams Alexandrea S, Mead Brittany S, Scarola Gregory T, Kercher Kent W, Augenstein Vedra A, Heniford B Todd

机构信息

Division of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC. Electronic address: https://twitter.com/WLorenzjr.

Division of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC. Electronic address: https://twitter.com/AlexisHollandMD.

出版信息

Surgery. 2025 Mar;179:108895. doi: 10.1016/j.surg.2024.08.054. Epub 2024 Oct 28.

DOI:10.1016/j.surg.2024.08.054
PMID:39472265
Abstract

BACKGROUND

Inguinal hernia repair is one of the most common surgical procedures in the world. Each repair technique, open, laparoscopic, and robotic, has its advantages and advocates. Prior studies have compared 2 techniques, but there are little data comparing all 3 approaches with long-term follow-up.

METHODS

Prospectively collected data for unilateral inguinal hernia repair between 2007 and 2022 were reviewed. Using more than 3,300 inguinal hernia repairs, a 1:1:1 propensity score match was performed for open inguinal hernia repair, laparoscopic inguinal hernia repair, and robotic inguinal hernia repair based on patient age, sex, body mass index, and laterality. Standard descriptive and comparative statistics were performed. Data below is reported consistently as open inguinal hernia repair versus laparoscopic inguinal hernia repair versus robotic inguinal hernia repair.

RESULTS

A total of 420 patients were matched, with 140 in each group. There was no difference in age, body mass index, or smoking status between groups. Open inguinal hernia repair had significantly more comorbidities (2.8 vs 2.6 vs 2.3; P = .035), including higher rates of chronic obstructive pulmonary disease (5.0% vs 0.0% vs 1.4%; P = .013), cirrhosis (4.3% vs 0.0% vs 1.4%; P = .032), and congestive heart failure (5.0% vs 0.7% vs 0.7%; P = .023). American Society of Anesthesiologists scores differed significantly between groups (stage III and IV: 35.0% vs 20.0% vs 28.6%; P = .004). Open inguinal hernia repair were more often recurrent (48.6% vs 27.9% vs 17.1%; P < .001). The mean operative time was significantly different between groups (88.0 vs 86.1 vs 101.4 minutes; P < .001). There was no difference in wound infection (0.7% vs 0.0% vs 0.0%; P > .99), hematoma (1.4% vs 0.7% vs 1.4%; P > .99), seroma requiring intervention (2.9% vs 0.7% vs 0.7%; P = .377), or readmission (0.0% vs 2.1% vs 1.4%; P = .378). The rate of prolonged discomfort, requiring more than 2 pain medication refills, was similar between groups (2.9% vs 2.1% vs 2.1%; P = .903). Robotic inguinal hernia repair was significantly more expensive than laparoscopic inguinal hernia repair and open inguinal hernia repair ($10,005 ± $7,050 vs $17,155 ± $6,702 vs $31,173 ± $8,474; P < .001). With follow-up of at least 2.4 years in each group (3.6 vs 4.8 vs 2.4 years; P < .001), the recurrence rate was comparable (3.6% vs 0.7% vs 0.7%; P = .226).

CONCLUSIONS

All techniques are safe and effective in qualified hands. Open inguinal hernia repair was more commonly used in comorbid patients and recurrent hernias, but the techniques had comparable rates of wound complications, postoperative prolonged discomfort, and recurrence.

摘要

背景

腹股沟疝修补术是世界上最常见的外科手术之一。每种修补技术,开放手术、腹腔镜手术和机器人手术,都有其优点和支持者。先前的研究比较了两种技术,但很少有数据对所有三种方法进行长期随访比较。

方法

回顾了2007年至2022年间前瞻性收集的单侧腹股沟疝修补术数据。基于患者年龄、性别、体重指数和疝侧别,对3300多例腹股沟疝修补术进行了开放腹股沟疝修补术、腹腔镜腹股沟疝修补术和机器人腹股沟疝修补术的1:1:1倾向评分匹配。进行了标准的描述性和比较性统计。以下数据始终报告为开放腹股沟疝修补术与腹腔镜腹股沟疝修补术与机器人腹股沟疝修补术的对比。

结果

总共匹配了420例患者,每组140例。各组之间在年龄、体重指数或吸烟状况方面没有差异。开放腹股沟疝修补术的合并症明显更多(2.8比2.6比2.3;P = 0.035),包括慢性阻塞性肺疾病的发生率更高(5.0%比0.0%比1.4%;P = 0.013)、肝硬化(4.3%比0.0%比1.4%;P = 0.032)和充血性心力衰竭(5.0%比0.7%比0.7%;P = 0.023)。美国麻醉医师协会评分在各组之间有显著差异(III期和IV期:35.0%比20.0%比28.6%;P = 0.004)。开放腹股沟疝修补术的复发率更高(48.6%比27.9%比17.1%;P < 0.001)。各组之间的平均手术时间有显著差异(88.0比86.1比101.4分钟;P < 0.001)。伤口感染(0.7%比0.0%比0.0%;P > 0.99)、血肿(1.4%比0.7%比1.4%;P > 0.99)、需要干预的血清肿(2.9%比0.7%比0.7%;P = 0.377)或再次入院(0.0%比2.1%比1.4%;P = 0.378)方面没有差异。需要超过2次补充止痛药的长期不适发生率在各组之间相似(2.9%比2.1%比2.1%;P = 0.903)。机器人腹股沟疝修补术比腹腔镜腹股沟疝修补术和开放腹股沟疝修补术显著更昂贵(10,005美元±7,050美元比17,155美元±6,702美元比31,173美元±8,474美元;P < 0.001)。每组至少随访2.4年(3.6比4.8比2.4年;P < 0.001),复发率相当(3.6%比0.7%比0.7%;P = 0.226)。

结论

在技术熟练的医生手中,所有技术都是安全有效的。开放腹股沟疝修补术在合并症患者和复发性疝中更常用,但这些技术在伤口并发症、术后长期不适和复发率方面相当。

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