Department of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Department of Radiology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Korean J Radiol. 2024 Nov;25(11):942-958. doi: 10.3348/kjr.2024.0871.
Active surveillance (AS) has been widely adopted as an alternative to immediate surgery owing to the indolent nature and favorable outcomes of papillary thyroid microcarcinoma (PTMC). AS is generally recommended for tumors measuring ≤1 cm without aggressive cytological subtypes, risk of gross extrathyroidal extension (ETE), lymph node metastasis (LNM), or distant metastasis. AS requires careful patient selection based on various patient and tumor characteristics, and ultrasound (US) findings. Moreover, during AS, regular US is performed to monitor any signs of tumor progression, including tumor growth, new US features of potential gross ETE, and LNM. Therefore, appropriate imaging-based assessment plays a crucial role in determining whether AS or surgery should be pursued. However, detailed recommendations concerning US evaluation are currently insufficient, necessitating the formulation of this guideline. The Korean Society of Thyroid Radiology has developed a consensus statement for low-risk PTMC, covering US assessment methods when considering AS as a management option and conducting follow-up imaging tests during AS. This guideline aims to provide optimal scientific evidence and expert opinion consensus regarding a standardized US-based assessment protocol for low-risk PTMC.
主动监测(AS)由于甲状腺微小乳头状癌(PTMC)的惰性性质和良好的结果,已被广泛应用于替代立即手术。AS 通常推荐用于无侵袭性细胞学亚型、甲状腺外侵犯(ETE)、淋巴结转移(LNM)或远处转移风险的直径≤1cm 的肿瘤。AS 需要根据各种患者和肿瘤特征以及超声(US)检查结果进行仔细的患者选择。此外,在 AS 期间,定期进行 US 检查以监测肿瘤进展的任何迹象,包括肿瘤生长、潜在的 gross ETE 的新 US 特征和 LNM。因此,适当的基于成像的评估在确定是否应进行 AS 或手术方面起着至关重要的作用。然而,目前关于 US 评估的详细建议还不够充分,因此需要制定本指南。韩国甲状腺放射学会制定了低风险 PTMC 的共识声明,涵盖了在考虑 AS 作为管理选择时的 US 评估方法以及在 AS 期间进行随访成像检查。本指南旨在为低风险 PTMC 的标准化基于 US 的评估方案提供最佳的科学证据和专家意见共识。