Yokoyama Koji, Yakuo Toshinari, Mamada Mitsukazu
Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN.
Cureus. 2024 Sep 28;16(9):e70407. doi: 10.7759/cureus.70407. eCollection 2024 Sep.
Kawasaki disease (KD) is a common vasculitis syndrome that mainly affects children. Latent tuberculosis infection (LTBI) is a tuberculosis (TB) infection without signs or symptoms. Here, we report the case of a boy who traveled from abroad, was diagnosed with KD at our hospital, and underwent multidisciplinary treatment, including anti-TNFα therapy. Subsequently, the patient was found to have LTBI and was administered anti-TB treatment. To the best of our knowledge, this is the first reported case of LTBI in a KD patient receiving immunosuppressive therapy containing anti-TNFα.
川崎病（KD）是一种主要影响儿童的常见血管炎综合征。潜伏性结核感染（LTBI）是一种没有体征或症状的结核（TB）感染。在此，我们报告一例从国外前来就诊的男孩病例，该男孩在我院被诊断为川崎病，并接受了包括抗TNFα治疗在内的多学科治疗。随后，该患者被发现患有潜伏性结核感染，并接受了抗结核治疗。据我们所知，这是首例报道的在接受含抗TNFα免疫抑制治疗的川崎病患者中发生潜伏性结核感染的病例。
