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人参的植物化学成分和生物活性的综合评价。

A Comprehensive Review of the Phytochemical Constituents and Bioactivities of .

机构信息

Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal.

Natural Product Chemistry, Center for Natural and Applied Sciences, Kathmandu, Nepal.

出版信息

ScientificWorldJournal. 2024 Oct 22;2024:8895039. doi: 10.1155/2024/8895039. eCollection 2024.

Abstract

, commonly known as Tulsi, is revered in Ayurveda for its extensive medicinal properties. However, there is a need to consolidate current knowledge on its phytochemical constituents and their pharmacological activities to identify potential areas for further research and drug development. This review aims to bridge this gap by providing a comprehensive analysis of the bioactive secondary metabolites found in , such as rosmarinic acid, oleanolic acid, luteolin, ursolic acid, and limonene, and their associated therapeutic effects. The review will highlight the pharmacological importance of these metabolites, which exhibit antioxidant, neuroprotective, anticancer, and anti-inflammatory properties. Additionally, this study will explore the plant's wide range of beneficial qualities, including anti-inflammatory, antioxidant, anticholinergic, pain-relieving, antimicrobial, stress-reducing, antidiabetic, anticancer, liver-protective, ulcer-inhibiting, antifungal, and wound-healing attributes. Furthermore, this review focuses on the plant's potential in treating conditions such as asthma, persistent fever, tuberculosis, malaria, skin discoloration, itching, digestive issues, hemorrhoids, bone fractures, gout, urinary tract infection, and diabetes. By reviewing the current literature, the aim is to identify the gaps in the existing research and propose directions for future studies. This comprehensive review will serve as a valuable resource for researchers in the development and investigation of novel drugs derived from .

摘要

圣罗勒,通常被称为 Tulsi,因其广泛的药用特性在印度阿育吠陀医学中备受推崇。然而,有必要整合其植物化学成分及其药理学活性的现有知识,以确定进一步研究和药物开发的潜在领域。本综述旨在通过分析圣罗勒中发现的生物活性次生代谢物,如迷迭香酸、齐墩果酸、木犀草素、熊果酸和柠檬烯,及其相关的治疗作用,来填补这一空白。综述将强调这些代谢物的药理学重要性,它们具有抗氧化、神经保护、抗癌和抗炎特性。此外,本研究还将探讨该植物的广泛有益特性,包括抗炎、抗氧化、抗胆碱能、止痛、抗菌、减轻压力、抗糖尿病、抗癌、保肝、抑制溃疡、抗真菌和促进伤口愈合的特性。此外,本综述还重点介绍了该植物在治疗哮喘、持续发热、肺结核、疟疾、皮肤变色、瘙痒、消化问题、痔疮、骨折、痛风、尿路感染和糖尿病等疾病方面的潜力。通过回顾现有文献,旨在确定现有研究中的差距,并为未来的研究提出方向。本综述将为研究人员开发和研究源自圣罗勒的新型药物提供有价值的资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e19/11521583/762edb0f5e69/TSWJ2024-8895039.001.jpg

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