Govindarajan Krishna Kumar
Department of Pediatric Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry 605006, India.
World J Clin Oncol. 2024 Oct 24;15(10):1376-1378. doi: 10.5306/wjco.v15.i10.1376.
Gut dysbiosis, a phenomenon in which the existing commensal microbiome changes to an adverse microenvironment in the colon, is thought to lead to altered cellular signals. How this is involved in producing mucosal outgrowths such as polyps in the colon is intriguing. Deciphering the various mechanisms involved provides an in-depth understanding of the link between gut dysbiosis and colonic polyps.
肠道微生物群失调是指现存的共生微生物群转变为结肠内的不良微环境的一种现象,被认为会导致细胞信号改变。其如何参与导致结肠息肉等黏膜增生仍很有趣。解读其中涉及的各种机制有助于深入理解肠道微生物群失调与结肠息肉之间的联系。