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本文引用的文献

1
Identification of taxonomic changes in the fecal bacteriome associated with colorectal polyps and cancer: potential biomarkers for early diagnosis.与结直肠息肉和癌症相关的粪便细菌群落分类学变化的鉴定：早期诊断的潜在生物标志物。
Front Microbiol. 2024 Jan 11;14:1292490. doi: 10.3389/fmicb.2023.1292490. eCollection 2023.
2
Intestinal dysbiosis as an intraoperative predictor of septic complications: evidence from human surgical cohorts and preclinical models of peritoneal sepsis.肠道菌群失调作为脓毒症并发症的术中预测指标：来自人类外科队列和腹膜脓毒症临床前模型的证据。
Sci Rep. 2023 Dec 21;13(1):22921. doi: 10.1038/s41598-023-49034-z.
3
Volatile Markers for Cancer in Exhaled Breath-Could They Be the Signature of the Gut Microbiota?呼气中癌症的挥发性标志物——它们可能是肠道微生物组的特征吗？
Molecules. 2023 Apr 15;28(8):3488. doi: 10.3390/molecules28083488.
4
Progress of gut microbiome and its metabolomics in early screening of colorectal cancer.肠道微生物组及其代谢组学在结直肠癌早期筛查中的研究进展。
Clin Transl Oncol. 2023 Jul;25(7):1949-1962. doi: 10.1007/s12094-023-03097-6. Epub 2023 Feb 15.
5
Familial adenomatous polyposis and changes in the gut microbiota: New insights into colorectal cancer carcinogenesis.家族性腺瘤性息肉病与肠道微生物群的变化：对结直肠癌致癌作用的新见解。
World J Gastrointest Oncol. 2021 Jun 15;13(6):495-508. doi: 10.4251/wjgo.v13.i6.495.
6
An Overview of Gut Microbiota and Colon Diseases with a Focus on Adenomatous Colon Polyps.肠道微生物群与结肠疾病概述，重点关注腺瘤性结肠息肉。
Int J Mol Sci. 2020 Oct 5;21(19):7359. doi: 10.3390/ijms21197359.
7
The association between fecal microbiota and different types of colorectal polyp as precursors of colorectal cancer.粪便微生物群与不同类型结直肠息肉作为结直肠癌前体的关系。
Microb Pathog. 2018 Nov;124:244-249. doi: 10.1016/j.micpath.2018.08.035. Epub 2018 Aug 22.

肠道菌群失调与结肠腺瘤：致命关联？

Dysbiosis and colonic adenoma: The lethal link?

作者信息

Govindarajan Krishna Kumar

机构信息

Department of Pediatric Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry 605006, India.

出版信息

World J Clin Oncol. 2024 Oct 24;15(10):1376-1378. doi: 10.5306/wjco.v15.i10.1376.

DOI:10.5306/wjco.v15.i10.1376
PMID:39473869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11514503/
Abstract

Gut dysbiosis, a phenomenon in which the existing commensal microbiome changes to an adverse microenvironment in the colon, is thought to lead to altered cellular signals. How this is involved in producing mucosal outgrowths such as polyps in the colon is intriguing. Deciphering the various mechanisms involved provides an in-depth understanding of the link between gut dysbiosis and colonic polyps.

摘要

肠道微生物群失调是指现存的共生微生物群转变为结肠内的不良微环境的一种现象，被认为会导致细胞信号改变。其如何参与导致结肠息肉等黏膜增生仍很有趣。解读其中涉及的各种机制有助于深入理解肠道微生物群失调与结肠息肉之间的联系。