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肠道微生物群与结肠疾病概述,重点关注腺瘤性结肠息肉。

An Overview of Gut Microbiota and Colon Diseases with a Focus on Adenomatous Colon Polyps.

机构信息

Department of Food Science, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.

Regional Institute of Gastroenterology and Hepatology "Prof. Dr. Octavian Fodor", 400158 Cluj-Napoca, Romania.

出版信息

Int J Mol Sci. 2020 Oct 5;21(19):7359. doi: 10.3390/ijms21197359.

DOI:10.3390/ijms21197359
PMID:33028024
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7582333/
Abstract

It is known and accepted that the gut microbiota composition of an organism has an impact on its health. Many studies deal with this topic, the majority discussing gastrointestinal health. Adenomatous colon polyps have a high prevalence as colon cancer precursors, but in many cases, they are hard to diagnose in their early stages. Gut microbiota composition correlated with the presence of adenomatous colon polyps may be a noninvasive and efficient tool for diagnosis with a high impact on human wellbeing and favorable health care costs. This review is meant to analyze the gut microbiota correlated with the presence of adenomatous colon polyps as the first step for early diagnosis, prophylaxis, and treatment.

摘要

众所周知,生物体的肠道微生物组成会对其健康产生影响。许多研究都涉及这个主题,其中大多数讨论的是胃肠道健康。腺瘤性结肠息肉是结肠癌的高发前体,但在许多情况下,它们在早期很难诊断。与腺瘤性结肠息肉存在相关的肠道微生物组成可能是一种非侵入性且有效的诊断工具,对提高人类健康水平和降低医疗保健成本具有重要意义。本综述旨在分析与腺瘤性结肠息肉存在相关的肠道微生物群,作为早期诊断、预防和治疗的第一步。

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