Shi Yuxin, Gong Yongli, Guan Yurong, Tang Jiawei
Computer School, Hubei Polytechnic University, Huangshi, China.
College of Computer Science, Huanggang Normal University, Huanggang, China.
Front Psychiatry. 2024 Oct 14;15:1395243. doi: 10.3389/fpsyt.2024.1395243. eCollection 2024.
This study aims to explore an autoencoder-based method for generating brain MRI images of patients with Autism Spectrum Disorder (ASD) and non-ASD individuals, and to discriminate ASD based on the generated images. Initially, we introduce the research background of ASD and related work, as well as the application of deep learning in the field of medical imaging. Subsequently, we detail the architecture and training process of the proposed autoencoder model, and present the results of generating MRI images for ASD and non-ASD patients. Following this, we designed an ASD classifier based on the generated images and elucidated its structure and training methods. Finally, through analysis and discussion of experimental results, we validated the effectiveness of the proposed method and explored future research directions and potential clinical applications. This research offers new insights and methodologies for addressing challenges in ASD studies using deep learning technology, potentially contributing to the automated diagnosis and research of ASD.
本研究旨在探索一种基于自动编码器的方法,用于生成自闭症谱系障碍(ASD)患者和非ASD个体的脑部磁共振成像(MRI)图像,并基于生成的图像对ASD进行鉴别。首先,我们介绍了ASD的研究背景和相关工作,以及深度学习在医学成像领域的应用。随后,我们详细阐述了所提出的自动编码器模型的架构和训练过程,并展示了为ASD和非ASD患者生成MRI图像的结果。在此之后,我们基于生成的图像设计了一个ASD分类器,并阐明了其结构和训练方法。最后,通过对实验结果的分析和讨论,我们验证了所提出方法的有效性,并探索了未来的研究方向和潜在的临床应用。这项研究为利用深度学习技术应对ASD研究中的挑战提供了新的见解和方法,有可能为ASD的自动化诊断和研究做出贡献。