Pang Guobao, Wang Chenyan, Wang Xiaojun, Li Xiaona, Meng Qiaoyu
Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China.
Front Bioeng Biotechnol. 2024 Oct 15;12:1455027. doi: 10.3389/fbioe.2024.1455027. eCollection 2024.
The cornea is a vital tissue of the human body. The health status of the cornea has a great impact on the quality life of person. There has been a great deal of research on the human cornea biomechancis. However, the difficulty in obtaining the human cornea has greatly limited the research of cornea biomechancis. Using finite element modelling has become a very effective and economical means for studying mechanical properties of human cornea. In this review, the geometrical and constitutive models of the cornea are summarised and analysed, respectively. Some factors affecting of the finite element calculation are discussed. In addition, prospects and challenges for the finite element model of the human cornea are presented. This review will be helpful to researchers performing studies in the relevant fields of human cornea finite element analysis.
角膜是人体的重要组织。角膜的健康状况对人的生活质量有很大影响。关于人体角膜生物力学已经有大量研究。然而,获取人体角膜的困难极大地限制了角膜生物力学的研究。使用有限元建模已成为研究人体角膜力学特性非常有效且经济的手段。在这篇综述中,分别总结并分析了角膜的几何模型和本构模型。讨论了一些影响有限元计算的因素。此外,还介绍了人体角膜有限元模型的前景与挑战。这篇综述将有助于在人体角膜有限元分析相关领域开展研究的人员。