Buzard K A
Shearing Eye Institute, Las Vegas, Nev.
Refract Corneal Surg. 1992 Mar-Apr;8(2):127-38.
As refractive procedures involving the cornea have proliferated, concerns over the long-term stability and predictability of these procedures have occupied a more prominent role.
Procedures and principles of mechanical engineering to mathematically model the cornea can provide valuable insight into the biomechanics of the cornea, and this approach can be used to predict corneal behavior. In order to utilize these advanced methods, some basic knowledge concerning limitations, assumptions, and techniques regarding the finite element method is needed. The principles of mechanical measurement of deformable bodies are discussed, as are the quantities stress, strain, Poisson's ratio, and creep as they are measured and used in the modeling of biologic systems. The finite element modeling procedure is discussed in a simplified geometric system.
While work remains to be done in this area, it is seen that useful and predictive models can be created which significantly improve our understanding and predictability of corneal procedures.
随着涉及角膜的屈光手术不断增加,对这些手术的长期稳定性和可预测性的担忧变得更加突出。
用机械工程的程序和原理对角膜进行数学建模,可以为角膜生物力学提供有价值的见解,这种方法可用于预测角膜行为。为了运用这些先进方法,需要一些关于有限元方法的局限性、假设和技术的基础知识。讨论了可变形体的力学测量原理,以及应力、应变、泊松比和蠕变等在生物系统建模中测量和使用的量。在一个简化的几何系统中讨论了有限元建模程序。
虽然该领域仍有工作要做,但可以创建有用的预测模型,这将显著提高我们对角膜手术的理解和预测能力。