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1例合并眼部受累的梅毒:1例多发性硬化患者梅毒血清学持续阴性

A Case of Syphilis With Ocular Involvement: Persistent Negative Serology in a Patient With Multiple Sclerosis.

作者信息

Pipitò Luca, Ganci Irene, Cicero Andrea, Medaglia Alice Annalisa, D'Avenia Simona, Mandalà Edoardo, Calà Cinzia, Di Carlo Paola, Cascio Antonio

机构信息

Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G D'Alessandro," University of Palermo, Palermo, Italy.

Infectious and Tropical Disease Unit, Azienda Ospedaliera Universitaria Policlinico "P. Giaccone,"  Palermo, Italy.

出版信息

Open Forum Infect Dis. 2024 Oct 29;11(10):ofae563. doi: 10.1093/ofid/ofae563. eCollection 2024 Oct.

Abstract

Diagnostic algorithms for syphilis are based on serology. However, with the advent of immunosuppressive therapies, these algorithms may fail. We report a case of an individual with multiple sclerosis on treatment with ofatumumab and secondary syphilis with visual and auditory systems involvement and persistent negative treponemal and nontreponemal tests.

摘要

梅毒的诊断算法基于血清学。然而,随着免疫抑制疗法的出现,这些算法可能会失效。我们报告了一例患有多发性硬化症的患者,该患者正在接受奥法木单抗治疗,同时患有继发性梅毒,累及视觉和听觉系统,梅毒螺旋体和非梅毒螺旋体检测持续呈阴性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cc0a/11521249/1d82e435752c/ofae563f1.jpg

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