Faculty of Medicine, Scientific Circle of Neurology and Neurosurgery, Medical University of Gdansk, Gdansk, Poland.
Faculty of Medicine, Scientific Circle of Dermatology, Medical University of Gdansk, Gdansk, Poland.
Acta Derm Venereol. 2024 Oct 30;104:adv40459. doi: 10.2340/actadv.v104.40459.
Atopic dermatitis is often accompanied by a lack of sleep efficiency, which may impact neurocognitive functions. This review assesses the association between sleep quality in atopic dermatitis patients and neurocognitive decline. Databases searched included PubMed, Scopus, and Web of Science from inception to 8 January 2024, adhering to PRISMA guidelines. Cross-sectional and longitudinal studies were included. Records were screened and assessed for eligibility, with 13 studies included in the final analysis. From an initial pool of 4,529 records, 13 studies involving 272,868 participants met the inclusion criteria. The review identified a consistent pattern of sleep disruption in individuals with atopic dermatitis, which was associated with various short-term neurocognitive challenges such as impaired focus, decreased sleep efficiency, and lower IQ. Limited evidence was found for potential long-term cognitive decline associated with chronic atopic dermatitis. Lower sleep quality in atopic dermatitis is associated with neurocognitive deficits. While immediate effects are evident, further research is needed to understand potential long-term consequences. Integrating sleep management into atopic dermatitis care is imperative.
特应性皮炎常伴有睡眠效率低下，这可能会影响神经认知功能。本综述评估了特应性皮炎患者的睡眠质量与神经认知能力下降之间的关系。检索的数据库包括 PubMed、Scopus 和 Web of Science，时间从建库到 2024 年 1 月 8 日，遵循 PRISMA 指南。纳入了横断面和纵向研究。对记录进行了筛选和资格评估，最终分析纳入了 13 项研究。从最初的 4529 条记录中，有 13 项涉及 272868 名参与者的研究符合纳入标准。综述发现，特应性皮炎患者存在睡眠障碍的一致模式，这与各种短期神经认知挑战有关，如注意力不集中、睡眠效率降低和智商下降。有限的证据表明慢性特应性皮炎与潜在的认知能力下降有关。特应性皮炎患者的睡眠质量较差与神经认知缺陷有关。虽然即时效应明显，但仍需要进一步研究来了解潜在的长期后果。将睡眠管理纳入特应性皮炎的治疗中至关重要。
