北爱尔兰侵袭性皮肤恶性黑色素瘤的发病率及发病机制。
The incidence and pathogenesis of invasive cutaneous malignant melanoma in Northern Ireland.
作者信息
Gordon L G, Lowry W S
出版信息
Br J Cancer. 1986 Jan;53(1):75-80. doi: 10.1038/bjc.1986.11.
Abstract
Three hundred and four suspected cases of malignant melanoma diagnosed in Northern Ireland over a 5 year period have been reviewed. Two hundred and forty fulfilled the diagnostic criteria of invasive cutaneous malignant melanoma (CMM) and were accepted as suitable for analysis an incidence of 3.12. The female to male ratio for CMM in this study is 3:1. This excess of female lesions occurs at all major anatomical sites and for all tumour types. There are many thick melanomas in the province, and 67% of cases were greater than 1.7 mm thick. Each tumour type has a distinctive age curve. The implications of these findings are discussed. The evidence suggests that intrinsic factors are as important as extrinsic factors.
摘要
对北爱尔兰在5年期间诊断出的304例恶性黑色素瘤疑似病例进行了回顾。240例符合侵袭性皮肤恶性黑色素瘤（CMM）的诊断标准，并被认为适合进行分析，发病率为3.12。本研究中CMM的男女比例为3:1。这种女性病损的过量在所有主要解剖部位和所有肿瘤类型中均有发生。该省有许多厚的黑色素瘤，67%的病例厚度超过1.7毫米。每种肿瘤类型都有独特的年龄曲线。讨论了这些发现的意义。证据表明内在因素与外在因素同样重要。
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