Stalder J F, Dreno B, Bureau B, Hakim J
Br J Dermatol. 1986 Feb;114(2):251-4. doi: 10.1111/j.1365-2133.1986.tb02805.x.
Chronic granulomatous disease (CGD) is characterized by a bactericidal defect involving the oxidative metabolism of polymorphonuclear leukocytes (PML) and is most often transmitted as an X-linked trait. The cutaneous features of this disorder include infections and lupus-like rashes. These have been described in female carriers as well as in males with the disease. Two cases of siblings presenting an autosomal form of CGD syndrome, with lupus-like cutaneous manifestations, are reported here.
慢性肉芽肿病（CGD）的特征是涉及多形核白细胞（PML）氧化代谢的杀菌缺陷，且最常作为X连锁性状遗传。这种疾病的皮肤特征包括感染和狼疮样皮疹。女性携带者以及患病男性中均有此类情况的描述。本文报告了两例呈现常染色体形式CGD综合征且伴有狼疮样皮肤表现的同胞病例。
