Coté John J, Coté Remington D, Dilsaver Danielle B, Massey Suena H, Doehrman Pooja, Coté Brayden P, Kilzer Riley, Badura-Brack Amy S
CHI Health/CommonSpirit Health, 16909 Lakeside Hills Ct, Suite 401, Omaha, NE, USA.
Department of Obstetrics and Gynecology, Creighton University School of Medicine, Omaha, NE, USA.
3D Print Med. 2024 Oct 30;10(1):35. doi: 10.1186/s41205-024-00238-7.
Smoking in pregnancy continues to cause significant morbidity to mothers and babies and contributes to tremendous costs to society. Maternal-fetal attachment (MFA) may differentiate smokers who quit or pregnant smokers from non-smokers. Researchers have recommended utilizing interventions that improve MFA to help decrease smoking within pregnancy.
We performed a randomized clinical trial of pregnant smokers (n = 33) using an MFA-informed, intention-to-treat protocol. We recruited pregnant smokers and provided timeline follow back (TLFB) interviews from 27 weeks of pregnancy until 6 weeks post-partum. Salivary cotinine was also collected at five different time points. 3D ultrasonography was performed, and patients were randomly assigned a 3D picture or a 3D model of their fetus.
Overall, the average percent reduction in cigarette use was 37.03% (SD = 31.18). The main effect of 3D type was not significant (3D Model vs. 3D Print Estimate = -0.09, 95% CI: - 0.19 to 0.01, p = 0.066). A total of 4 patients (12%) quit smoking within one week of delivery. A 10% reduction in cigarette use was associated with a 30.57 g increase in birth weight (Estimate = 30.57, 95% CI: -14.15 to 75.29); a 10% reduction in cigarette use was associated with a 0.14 week increase in estimate gestational age at delivery (Estimate = 0.14, 95% CI: -0.01 to 0.28).
Patients who smoke in pregnancy decrease the number of cigarettes smoked after receiving either a 3D picture or 3D model of their fetus.
clinicaltrials.gov (NCT04541121).
孕期吸烟持续对母亲和婴儿造成严重伤害，并给社会带来巨大成本。母婴依恋（MFA）可能会区分戒烟的吸烟者或孕期吸烟者与非吸烟者。研究人员建议采用改善母婴依恋的干预措施，以帮助减少孕期吸烟。
我们对孕期吸烟者（n = 33）进行了一项基于母婴依恋的随机临床试验，并采用意向性分析方案。我们招募了孕期吸烟者，并从孕27周直至产后6周进行时间线追溯（TLFB）访谈。还在五个不同时间点收集了唾液可替宁。进行了三维超声检查，并为患者随机分配其胎儿的三维图片或三维模型。
总体而言，香烟使用量平均减少了37.03%（标准差 = 31.18）。三维类型的主要效应不显著（三维模型与三维打印估计值 = -0.09，95%置信区间：-0.19至0.01，p = 0.066）。共有4名患者（12%）在分娩后一周内戒烟。香烟使用量减少10%与出生体重增加30.57克相关（估计值 = 30.57，95%置信区间：-14.15至75.29）；香烟使用量减少10%与分娩时估计孕周增加0.14周相关（估计值 = 0.14，95%置信区间：-0.01至0.28）。
孕期吸烟的患者在收到其胎儿的三维图片或三维模型后，吸烟量会减少。
clinicaltrials.gov（NCT04541121）。
