Universidade Estadual Paulista "Júlio de Mesquita Filho", Faculdade de Medicina Veterinária de Araçatuba, Programa de Pós-Graduação em Saúde Animal, Araçatuba, SP, Brasil.
Universidade Estadual Paulista "Júlio de Mesquita Filho", Faculdade de Medicina Veterinária de Araçatuba, Departamento de Produção e Saúde Animal, Araçatuba, SP, Brasil.
Rev Soc Bras Med Trop. 2024 Oct 28;57:e004202024. doi: 10.1590/0037-8682-0170-2023. eCollection 2024.
Rabies is a zoonosis usually transmitted to mammals via contact between the saliva of infected animals and either the skin or mucosa of the attacked individual, and post-exposure prophylaxis (PEP) is the only way to avoid the disease. This study aimed to perform a descriptive analysis of PEP after attacks by dogs and cats in the state of São Paulo.
We analyzed the disease compulsory notification forms Human Anti-Rabies Care (CID10: W64), available in the Notifiable Diseases Information System (SINAN), from 2013 to 2017. Treatment adequacy was analyzed according to the parameters established by the Brazilian Health Ministry.
A total of 572,889 notifications were reported during the study period, 94.1% (538,975) of which corresponded to dog or cat attacks, with an occurrence of 26.9 cases per 10,000 inhabitants. Among the recommended procedures, the most frequent was the observation of the animals for 10 days (44.4%), which was adopted inappropriately at a lower frequency. Prophylactic conduct was adequate in 68.8% of the cases, but only 55.5% of the individuals received adequate treatment. More than 112 thousand individuals (31,4%) received a correct recommendation for PEP but did not receive adequate treatment, leading to 246,787 doses of the vaccine and 8,888 doses of rabies immunoglobulin administered without following the recommendations of the Ministry of Health.
The use of immunobiologicals is excessive, indicating the need for investment in training health professionals to follow the recommendations of the Ministry of Health.
狂犬病是一种通常通过感染动物的唾液与受攻击个体的皮肤或粘膜接触而在哺乳动物之间传播的动物源性传染病,暴露后预防(PEP)是避免这种疾病的唯一方法。本研究旨在对圣保罗州犬猫咬伤后进行 PEP 的描述性分析。
我们分析了 2013 年至 2017 年可在法定传染病报告信息系统(SINAN)中获得的人类狂犬病护理疾病强制报告表(CID10:W64)。根据巴西卫生部规定的参数分析治疗的适当性。
在研究期间共报告了 572,889 例病例通知,其中 94.1%(538,975 例)为犬或猫咬伤,每 10,000 居民中有 26.9 例发生。在所推荐的程序中,最常见的是观察动物 10 天(44.4%),但这种做法的频率较低且不适当。预防性措施在 68.8%的情况下是适当的,但只有 55.5%的个体接受了适当的治疗。超过 112,000 人(31.4%)接受了 PEP 的正确推荐,但未接受适当治疗,导致 246,787 剂疫苗和 8,888 剂狂犬病免疫球蛋白的使用,未遵循卫生部的建议。
免疫生物制剂的使用过多,表明需要投资培训卫生专业人员以遵循卫生部的建议。