School of Clinical Medicine, Shandong Second Medical University, Weifang, China.
Department of Prevention and Treatment of Chronic Non-communicable Diseases, Weifang Center for Disease Control and Prevention, Weifang, China.
PLoS One. 2024 Oct 30;19(10):e0312871. doi: 10.1371/journal.pone.0312871. eCollection 2024.
The objective of this study is to analyze the death characteristics and burden of disease (BOD) in diabetes mellitus (DM) patients in Weifang from 2010 to 2021. The findings will serve as a foundational data source and theoretical framework for public health administrative departments in the formulation of DM-related policies.
The annual percent change (APC) and average annual percent change (AAPC) of the disability-adjusted life years (DALY), years of life lost (YLL), and years lived with disability (YLD) in DM residents from 2010 to 2021 were analyzed using the Joinpoint software to reflect the changing trend of the BOD in DM patients. Additionally, we conducted an analysis of the various causes of death among these patients and compared BOD in diabetic patients with different backgrounds.
From 2010 to 2021, the burden of disease, which includes DALY, YL, and YLD, has been increasing among patients with DM in Weifang. It is noteworthy that the burden of disease is particularly pronounced among male patients and those aged 75 or above. Additionally, it is observed that widowed and illiterate DM patients have comparatively longer survival times. Furthermore, among the DM patients who have unfortunately passed away, it has been identified that unspecified DM with ketoacidosis accounts for 10.03% of the deaths as a direct cause of death. In contrast, type 2 diabetes mellitus (T2DM) with kidney complications contributes to 10.23% of the deaths as the fundamental cause of death.
The city is faced with a significant challenge of diabetes, which is influenced by factors such as gender, age, cultural background, and marital status. Unspecified diabetes mellitus (DM) with ketoacidosis (10.03%) and T2DM with renal complications (0.23%) are identified as the primary direct and underlying causes of death among diabetic patients, respectively. This study serves as a valuable reference for other regions in terms of diabetes prevention, control, and the management of chronic diseases.
本研究旨在分析 2010 年至 2021 年潍坊市糖尿病患者的死亡特征和疾病负担（BOD）。研究结果将为公共卫生行政部门制定糖尿病相关政策提供基础数据来源和理论框架。
采用 Joinpoint 软件分析 2010-2021 年糖尿病患者伤残调整生命年（DALY）、早死所致寿命损失年（YLL）和伤残所致健康寿命损失年（YLD）的年度变化百分比（APC）和平均年度变化百分比（AAPC），反映糖尿病患者 BOD 的变化趋势。此外，对患者的死因进行分析，并比较不同背景糖尿病患者的 BOD。
2010-2021 年，潍坊市糖尿病患者的疾病负担（包括 DALY、YLL 和 YLD）呈上升趋势。值得注意的是，男性和 75 岁及以上患者的疾病负担更为严重。此外，丧偶和文盲的糖尿病患者的生存时间相对较长。在不幸去世的糖尿病患者中，未特指的糖尿病伴酮症酸中毒是 10.03%的直接死亡原因，2 型糖尿病伴肾脏并发症是 10.23%的根本死亡原因。
该市面临着糖尿病的重大挑战，受性别、年龄、文化背景和婚姻状况等因素的影响。未特指的糖尿病伴酮症酸中毒（10.03%）和 2 型糖尿病伴肾脏并发症（0.23%）分别是糖尿病患者的主要直接和根本死亡原因。本研究为其他地区的糖尿病预防、控制和慢性病管理提供了参考。
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