National Institute for Health and Medical Research (INSERM) UMR 1219, Research Institute for Sustainable Development (IRD), Bordeaux Population Health Research Centre, Université de Bordeaux, Bordeaux, France
Center for Epidemiology and Research in Population Health (CERPOP), UMR 1295, Inserm, University Paul Sabatier Toulouse 3, Toulouse, France.
BMJ Paediatr Open. 2024 Oct 30;8(1):e002833. doi: 10.1136/bmjpo-2024-002833.
To describe antibiotic prescribing practices using the WHO AWaRe (, , ) classification in West African children under 5 years of age attending public primary health centres (PHCs).
Cross-sectional study.
The AIRE project implemented the systematic use of pulse oximetry into integrated management of childhood illness consultations in West African countries (Burkina Faso, Guinea, Mali and Niger). We described antibiotic prescriptions for outpatient children at 16 PHCs and for severe cases referred at district hospitals.
Between 14 June 2021 and 19 June 2022, 15 854 outpatients were included: 968 neonates and young infants (0-28 days) and 14 886 children (2-59 months). Among them, 78 (8.1%) neonates and young infants and 385 (2.6%) children were hospitalised. We evaluated 58 hospitalised neonates and young infants and 275 hospitalised children, respectively.
Frequency of antibiotic prescriptions according to the AWaRe classification recommended by WHO.
At the PHC level, proportions of neonates and young infants with ≥1 antibiotic prescription were 83%, 62%, 71% and 59% in Burkina Faso, Guinea, Mali and Niger, respectively. A total of 805 antibiotics were prescribed (85% and 13% ). The proportions of children with ≥1 antibiotic prescription reached 71%, 66%, 63% and 36% in Burkina Faso, Guinea, Mali and Niger, respectively. Out of the 9630 antibiotics prescribed, 93% were (mainly amoxicillin), and 7% . At the hospital level, antibiotics were mainly prescribed for severe cases referred. No antibiotics were prescribed.
High proportions of antibiotics were prescribed to outpatient children included, the appropriateness of which needs further study. Nevertheless, in every country, the proportion prescribed in the group reached the minimum threshold of 60% of all antibiotic prescriptions, as recommended by WHO.
PACTR202206525204526.
根据世界卫生组织 AWaRe（，，）分类，描述在西非 5 岁以下儿童中在公立初级保健中心（PHC）就诊时的抗生素处方情况。
横断面研究。
AIRE 项目在西非国家（布基纳法索、几内亚、马里和尼日尔）实施了将脉搏血氧仪系统地用于儿童疾病综合管理。我们描述了在 16 个 PHC 为门诊儿童和在区医院转诊的严重病例开出的抗生素处方。
2021 年 6 月 14 日至 2022 年 6 月 19 日期间，纳入了 15854 名门诊患者：968 名新生儿和婴儿（0-28 天）和 14886 名儿童（2-59 个月）。其中，78 名新生儿和婴儿和 385 名儿童住院。我们分别评估了 58 名住院新生儿和婴儿以及 275 名住院儿童。
根据世界卫生组织推荐的 AWaRe 分类，评估抗生素处方的频率。
在 PHC 层面，在布基纳法索、几内亚、马里和尼日尔，新生儿和婴儿中至少有 1 种抗生素处方的比例分别为 83%、62%、71%和 59%。共开出了 805 种抗生素（85%为 和 13%为 ）。在布基纳法索、几内亚、马里和尼日尔，儿童中至少有 1 种抗生素处方的比例分别为 71%、66%、63%和 36%。在开出的 9630 种抗生素中，93%为 （主要为阿莫西林），7%为 。在医院层面，主要为转诊的严重病例开出抗生素。未开出 。
为包括门诊儿童开出了较高比例的抗生素，其适当性需要进一步研究。然而，在每个国家，按照世界卫生组织的建议，在 类中开出的抗生素比例都达到了所有抗生素处方的 60%的最低阈值。
PACTR202206525204526。
