Taleghani Pediatric Hospital, Golestan University of Medical Sciences, Gorgan, Iran.
Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
BMC Pediatr. 2024 Oct 30;24(1):689. doi: 10.1186/s12887-024-05180-5.
Autism Spectrum Disorder (ASD) is a neurodevelopmental condition marked by difficulties in social interaction, communication, and repetitive behaviors or restricted interests. Although research on the link between ASD and parasitic diseases is limited, immune deficiency and inflammation may contribute to the development of parasitic infections.
We admitted a 14-year-old boy to the hospital who had a known history of ASD because he was presenting with respiratory symptoms, including cough and hemoptysis. During his time in the hospital, after conducting a series of tests and evaluations, we made a critical diagnosis of co-infection of lophomonas, tuberculosis, and hydatid cyst. In response to this diagnosis, we initiated a treatment plan that involved administering appropriate antibiotics as well as preparing for surgical intervention.
This case report highlights the complexities and challenges of managing such a rare combination of co-infections with TB, pulmonary hydatid disease and lophomonas in a pediatric patient with underlying developmental considerations such as ASD.
自闭症谱系障碍（ASD）是一种神经发育障碍，其特征是社交互动、沟通以及重复行为或受限兴趣方面存在困难。尽管 ASD 与寄生虫病之间的关联研究有限，但免疫缺陷和炎症可能导致寄生虫感染的发展。
我们收治了一名 14 岁的男孩，他已知患有 ASD，因出现呼吸症状，包括咳嗽和咯血而入院。在住院期间，经过一系列检查和评估，我们做出了一个重要诊断，即同时感染滴虫、肺结核和包虫囊肿。针对这一诊断，我们启动了一个治疗计划，包括使用适当的抗生素以及准备手术干预。
本病例报告强调了在患有 ASD 等发育相关疾病的儿科患者中，管理 TB、肺包虫病和滴虫这三种罕见病原体合并感染的复杂性和挑战。
