Sharma Rajat, Lonare Siddharth B, Nagar Saurabh, Badhal Sushant, Anand Samir
General Surgery, Maharishi Markandeshwar Medical College and Hospital, Solan, IND.
General Surgery, B. J. Government Medical College and Sassoon General Hospital, Pune, IND.
Cureus. 2024 Oct 30;16(10):e72701. doi: 10.7759/cureus.72701. eCollection 2024 Oct.
Most research on fistula-in-ano (FIA) is being done to improve surgical outcomes and reduce complications. Cyanoacrylate glue (CAG) is one of the promising options. We evaluated the efficacy and efficiency of CAG in the treatment of FIA.
A cohort of 30 patients were included who underwent treatment using CAG. Each patient followed up at one, three, and six months to evaluate improvement in pain, discomfort, and recurrence. Patients with recurrence were treated with fistulectomy.
The mean age of the cohort was 48.2±14.5 years, with a male-to-female ratio of 6:1, having four diabetic patients. Inter-sphincteric (16.54%) and trans-sphincteric (13.43%) fistulae were more common than extra-sphincteric (1.4%) fistula. The efficacy of CAG was 73%, and the procedure was found efficient with significant improvement in discomfort (p-value: 0.017). The recurrence rate was 27%, which occurred more in diabetic patients (p-value: 0.001) and trans-sphincteric fistula (p-value: 0.035). Conclusion: The CAG application is a simple and safe daycare procedure. However, the incidence of discharge and relief in pain was significantly less, but it cannot be advised to every patient of FIA. A young patient without comorbidities and with inter-sphincteric low fistula can best be treated by this method.
大多数关于肛瘘（FIA）的研究旨在改善手术效果并减少并发症。氰基丙烯酸酯胶水（CAG）是一种有前景的选择。我们评估了CAG治疗肛瘘的疗效和效率。
纳入30例接受CAG治疗的患者。每位患者在1个月、3个月和6个月进行随访，以评估疼痛、不适和复发情况的改善。复发患者接受瘘管切除术治疗。
该队列的平均年龄为48.2±14.5岁，男女比例为6:1，有4例糖尿病患者。括约肌间型（16.54%）和经括约肌型（13.43%）肛瘘比括约肌外型（1.4%）肛瘘更常见。CAG的疗效为73%，该手术被发现有效，不适情况有显著改善（p值：0.017）。复发率为27%，在糖尿病患者（p值：0.001）和经括约肌型肛瘘患者中（p值：0.035）复发更多。结论：应用CAG是一种简单安全的日间手术。然而，分泌物排出和疼痛缓解的发生率明显较低，但不能建议每位肛瘘患者都采用这种方法。对于无合并症且为括约肌间型低位肛瘘的年轻患者，这种方法治疗效果最佳。
