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免疫功能正常患者的多灶性皮肤结核:一例报告

Multifocal Cutaneous Tuberculosis in an Immunocompetent Patient: A Case Report.

作者信息

Mei Youming, Wang Hongsheng

机构信息

Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, People's Republic of China.

Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Nanjing, People's Republic of China.

出版信息

Infect Drug Resist. 2024 Oct 25;17:4633-4636. doi: 10.2147/IDR.S482501. eCollection 2024.

DOI:10.2147/IDR.S482501
PMID:39479401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11522008/
Abstract

Cutaneous tuberculosis is an infection caused by , the rare and the bacillus Calmette-Guérin vaccine. This disease has many clinical types with diverse clinical manifestations, mainly includes lupus vulgaris, tuberculosis verrucosa cutis, orificial tuberculosis and scrofuloderma that are difficult to identify. We report a case of cutaneous tuberculosis in a female who presented with disseminated papular and nodular lesions on her face and hands. The results of skin biopsy, PCR, and IGRA test contributed to the diagnosis. All lesions were resolved leaving only superficial scars after 5 months treatment.

摘要

皮肤结核是由[此处原文缺失病原体名称]、罕见的[此处原文缺失病原体名称]以及卡介苗引起的一种感染。这种疾病有许多临床类型,临床表现多样,主要包括寻常狼疮、疣状皮肤结核、腔口结核和皮肤瘰疬,难以鉴别。我们报告一例女性皮肤结核病例,该患者面部和手部出现播散性丘疹和结节性损害。皮肤活检、聚合酶链反应(PCR)和干扰素-γ释放试验(IGRA)的结果有助于诊断。经过5个月的治疗,所有损害均消退,仅留下浅表瘢痕。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2786/11522008/d51274902c77/IDR-17-4633-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2786/11522008/2ba5a2f05a4d/IDR-17-4633-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2786/11522008/908f5463379d/IDR-17-4633-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2786/11522008/d51274902c77/IDR-17-4633-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2786/11522008/2ba5a2f05a4d/IDR-17-4633-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2786/11522008/908f5463379d/IDR-17-4633-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2786/11522008/d51274902c77/IDR-17-4633-g0003.jpg

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本文引用的文献

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Genomic characteristics of isolates of cutaneous tuberculosis.皮肤结核分离株的基因组特征
Front Microbiol. 2023 May 17;14:1165916. doi: 10.3389/fmicb.2023.1165916. eCollection 2023.
2
Global prevalence of drug-resistant tuberculosis: a systematic review and meta-analysis.全球耐药结核病患病率:系统评价和荟萃分析。
Infect Dis Poverty. 2023 May 25;12(1):57. doi: 10.1186/s40249-023-01107-x.
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Clinicoepidemiological characteristics of cutaneous tuberculosis in 1458 Indian patients: a retrospective analytical study from a tertiary care center.
1458 例印度患者皮肤结核的临床流行病学特征:来自三级护理中心的回顾性分析研究。
Int J Dermatol. 2022 Aug;61(8):1012-1022. doi: 10.1111/ijd.16267. Epub 2022 May 17.
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An Bras Dermatol. 2022 Mar-Apr;97(2):129-144. doi: 10.1016/j.abd.2021.07.004. Epub 2022 Jan 4.
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The Search for a Uniformly Effective Treatment in Patients With Lupus Miliaris Disseminatus Faciei.寻找播散性粟粒性狼疮患者的统一有效治疗方法。
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Cutaneous tuberculosis: A great imitator.皮肤结核:一个伟大的模仿者。
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Epidemiology of extrapulmonary tuberculosis in the United States, 1993-2006.1993 - 2006年美国肺外结核病流行病学
Clin Infect Dis. 2009 Nov 1;49(9):1350-7. doi: 10.1086/605559.
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The role of fine-needle aspiration cytology and Ziehl Neelsen staining in the diagnosis of cutaneous tuberculosis.
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Standard classification of rosacea: Report of the National Rosacea Society Expert Committee on the Classification and Staging of Rosacea.酒渣鼻的标准分类:美国酒渣鼻协会分类与分期专家委员会报告
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