Yin Jie, Cheng Xinyu, Zhou Chendi, Xu Lin, Yang Bo, Yuan Ti-Fei
School of Psychology, Beijing Sport University, Beijing, China.
Laboratory of Sports Stress and Adaptation of General Administration of Sport, Beijing Sport University, Beijing, China.
Front Psychiatry. 2024 Oct 16;15:1416342. doi: 10.3389/fpsyt.2024.1416342. eCollection 2024.
Individuals with substance use disorder (SUD) are characterized by loss of control in drug use, such as increased impulsivity. Methamphetamine and methcathinone are psychostimulants, the use of which is accompanied by a high level of impulsivity. Whether individuals with methamphetamine use disorder (MUD) and methcathinone use disorder (MCUD) differ in different aspects of impulsivity is unclear.
We investigated impulsivity traits and behaviors in individuals with MUD and MCUD. The Barratt Impulsiveness Scale (BIS), Sensation Seeking Scale (SSS), and delay discounting task (DDT) were assessed in individuals with MUD and MCUD and in healthy controls (HCs); then, we performed network-based analysis and computational modeling to understand the potential differences among the three groups.
MUD subjects scored higher than MCUD subjects in terms of motor impulsivity, nonplanning impulsivity, and total BIS scores. The network analysis revealed that there were no significant differences between MUD and MCUD subjects in any centrality indices. The discount rate of MUD and MCUD subjects was significantly greater than that of HCs, whereas there was no difference in the discount rate between the two addiction groups.
These findings suggest that MUD and MCUD participants differ in impulsivity traits but not in impulsive behaviors, implying that impulsive traits and behaviors represent different aspects of impulsivity.
物质使用障碍（SUD）个体的特征是在药物使用方面失去控制，例如冲动性增加。甲基苯丙胺和甲卡西酮是精神兴奋剂，使用这些药物时会伴有高度冲动性。甲基苯丙胺使用障碍（MUD）和甲卡西酮使用障碍（MCUD）个体在冲动性的不同方面是否存在差异尚不清楚。
我们调查了MUD和MCUD个体的冲动性特质和行为。对MUD和MCUD个体以及健康对照（HC）进行了巴拉特冲动性量表（BIS）、感觉寻求量表（SSS）和延迟折扣任务（DDT）评估；然后，我们进行了基于网络的分析和计算建模，以了解三组之间的潜在差异。
在运动冲动性、非计划性冲动性和BIS总分方面，MUD受试者得分高于MCUD受试者。网络分析显示，MUD和MCUD受试者在任何中心性指标上均无显著差异。MUD和MCUD受试者的折扣率显著高于HC，而两个成瘾组之间的折扣率没有差异。
这些发现表明，MUD和MCUD参与者在冲动性特质上存在差异，但在冲动行为上没有差异，这意味着冲动特质和行为代表了冲动性的不同方面。
