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Adding a New Piece to the ASGR1 Puzzle: ANGPTL3.

作者信息

Garcia-Arcos Itsaso

机构信息

SUNY Downstate Health Sciences University, Department of Medicine, Division of Pulmonary and Critical Care Medicine, Department of Cell Biology, Brooklyn, NY.

出版信息

Arterioscler Thromb Vasc Biol. 2024 Dec;44(12):2450-2452. doi: 10.1161/ATVBAHA.124.321882. Epub 2024 Oct 31.

Abstract
摘要

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本文引用的文献

1
ASGR1 Deficiency Inhibits Atherosclerosis in Western Diet-Fed Mice by Regulating Lipoprotein Metabolism and Promoting Cholesterol Efflux.
Arterioscler Thromb Vasc Biol. 2024 Dec;44(12):2428-2449. doi: 10.1161/ATVBAHA.124.321076. Epub 2024 Oct 10.
3
ASGR1 deficiency diverts lipids toward adipose tissue but results in liver damage during obesity.
Cardiovasc Diabetol. 2024 Jan 28;23(1):42. doi: 10.1186/s12933-023-02099-6.
4
Impact of Asialoglycoprotein Receptor and Mannose Receptor Deficiency on Murine Plasma N-glycome Profiles.
Mol Cell Proteomics. 2023 Sep;22(9):100615. doi: 10.1016/j.mcpro.2023.100615. Epub 2023 Jul 4.
5
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion.
Nature. 2022 Aug;608(7922):413-420. doi: 10.1038/s41586-022-05006-3. Epub 2022 Aug 3.
6
Hypomorphic ASGR1 modulates lipid homeostasis via INSIG1-mediated SREBP signaling suppression.
JCI Insight. 2021 Oct 8;6(19):e147038. doi: 10.1172/jci.insight.147038.
7
ANGPTL3 as therapeutic target.
Curr Opin Lipidol. 2021 Dec 1;32(6):335-341. doi: 10.1097/MOL.0000000000000789.
8
Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin.
J Biol Chem. 2021 Oct;297(4):101177. doi: 10.1016/j.jbc.2021.101177. Epub 2021 Sep 8.
9
Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating Low-Density Lipoproteins and Increasing Their Uptake by Macrophages.
J Am Heart Assoc. 2021 Feb 16;10(4):e018756. doi: 10.1161/JAHA.120.018756. Epub 2021 Feb 6.
10
Impact of protein glycosylation on lipoprotein metabolism and atherosclerosis.
Cardiovasc Res. 2021 Mar 21;117(4):1033-1045. doi: 10.1093/cvr/cvaa252.

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